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246047-72-3 (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium 11147261, aruthenium-catalysts compound, is more and more widely used in various fields.

246047-72-3, (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium is a ruthenium-catalysts compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

To a solution of 6a (45.0 mg, 0.07 mmol) in anhydrous CH2Cl2 (6.0 ml) was added 2ndgeneration Grubbs catalyst (53.4 mg, 0.06 mmol) and CuCl (I) (13.9 mg, 0.14 mmol)under nitrogen at 30 C and stirred for 3 h. The reaction mixture was concentrated invacuo, and the residue was purified by column chromatography on silica gel (hexane /CH2Cl2 = 1 / 1) to give 2e (28.9mg, 37%).Green crystals; mp 135-137 C (dec.); 1H NMR (270 MHz, CDCl3) delta 1.21 (d, J = 6.2Hz, 10H), 2.38-2.47 (m, 18H), 3.79 (s, 3H), 4.20 (s, 4H), 5.80-5.75 (m, 1H), 6.73 (s,1H), 7.06 (s, 4H), 16.32 (s, 1H); 19F NMR (466 MHz, CDCl3) delta -80.6 (3F) -109.9 (2F),-121.1 (4F), -121.7 (4F), -122.5 (2F), -125.9 (2F); 13C NMR (68 MHz, CDCl3) delta 21.9,22.5, 26.1, 26.4, 29.7, 30.3, 51.4, 56.0, 75.9, 76.2, 109.3, 116.8, 122.8, 123.8, 126.6,127.6, 128.7, 132.8, 137.3, 139.1, 147.1, 149.6, 209.6, 295.0; IR (FT) 3853, 3737, 3638,2935, 2856, 2363, 2326, 1581, 1455, 1187, 1104, 898, 747 cm-1; HRMS (FAB) m/z[M+H]+ calcd for C40H40Cl2F17N2O2Ru 1076.1239; found 1076.1250., 246047-72-3

Reference£º
Article; Kobayashi, Yuki; Suzumura, Naoki; Tsuchiya, Yuki; Goto, Machiko; Sugiyama, Yuya; Shioiri, Takayuki; Matsugi, Masato; Synthesis; vol. 49; 8; (2017); p. 1796 – 1807;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

Introduction of a new synthetic route about 246047-72-3

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(1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium, cas is 246047-72-3, it is a common heterocyclic compound, the ruthenium-catalysts compound, its synthesis route is as follows.,246047-72-3

To a solution of 9 (59.7 mg, 0.098 mmol) in anhydrous CH2Cl2 (6.0 ml) was added 2ndgeneration Grubbs catalyst (75.3 mg, 0.088 mmol) and CuCl (I) (19.8 mg, 0.20 mmol)under nitrogen at 30 C and stirred for 3 h. The reaction mixture was concentrated invacuo, and the residue was purified by column chromatography on silica gel (hexane /CH2Cl2 = 1 / 1) to give 2j (43.2 mg, 41%).Green crystals; mp 153-157 C; 1H NMR (270 MHz, CDCl3) delta 2.38 (s, 6H), 2.45 (s,12H), 4.21 (s, 1H), 4.90-4.82 (m, 1H), 6.62 (d, J = 12.4 Hz, 1H), 7.07 (s, 5H), 16.22 (s,1H); 19F NMR (466 MHz, CDCl3) delta -80.6 (3F), -106.3 (1F), -108.5 (2F), -121.4 (2F),-121.5 (2F), -122.6 (4F), -125.9 (2F); 13C NMR (68 MHz, CDCl3) delta 19.4, 20.9, 51.4,77.5, 102.8, 103.2, 122.3, 129.4, 139.1, 141.8, 155.8, 155.9, 158.3, 162.1, 209.2, 291.7;IR (FT) 3905, 3857, 3747, 3642, 3569, 2971, 2918, 2363, 2342, 1837, 1723, 1691, 1612,1586, 1486, 1424, 1293, 1213, 1156, 1104, 1029, 915, 846 cm-1; HRMS (FAB) m/z[M+H]+ calcd for C39H37Cl2F18N2ORu 1064.1039; found 1064.1049.

With the rapid development of chemical substances, we look forward to future research findings about 246047-72-3

Introduction of a new synthetic route about 246047-72-3

With the rapid development of chemical substances, we look forward to future research findings about 246047-72-3

After a 50 mL two-necked flask was purged with argon, a ligand 7b (10 mmol), CuCl (30 mmol, 3 eq) and 30 mL of dry DCM were sequentially added and the mixture was purged three times with argon to protect the closed system with an argon balloon. Ruthenium complex 1b (12 mmol) was added under argon atmosphere, and the reaction was carried out at room temperature for 0.5 hour. After the reaction was over, silica gel was added to the filtrate to produce sand. The crude product was obtained by silica gel column chromatography and then washed with methanol or pentane-DCM to obtain a green solid product 8b in a yield of 79%.

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Reference£º
Patent; Zannan Science And Technology (Shanghai) Co., Ltd.; Zhan Zhengyun; (102 pag.)CN104262403; (2017); B;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

Some tips on 246047-72-3

246047-72-3, The synthetic route of 246047-72-3 has been constantly updated, and we look forward to future research findings.

Example 4 – Synthesis of the complex 3 according to the invention The commercially available complex G (1.0 g, 1.18 mmol) was placed in a flask, to which methylene chloride was added (24 ml). This was followed by adding the compound of the formula: (141 mg, 1.17 mmol) and tricyclohexylphosphine (330 mg, 1.18 mmol). The resulting solution was stirred at a temperature of 40C for 5 hours. The reaction mixture was introduced at the top of a chromatographic column packed with silica gel (eluent: ethyl acetate/cyclohexane, 0 to 10 vol. ). After evaporating the solvents, the complex 3 was obtained as a green solid (797 mg, 82% yield). The NMR data are consistent with Example 3.

246047-72-3, The synthetic route of 246047-72-3 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; APEIRON SYNTHESIS S.A.; SKOWERSKI, Krzysztof; BIENIEK, Micha?; WO2014/16422; (2014); A1;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

Introduction of a new synthetic route about (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium

With the rapid development of chemical substances, we look forward to future research findings about 246047-72-3

A suspension of 218 mg (0.26 mmol) of [RuCl2(PCy3) (ImH2Mes)(phenylmethy- lene)], 26 mg (0.26 mmol) copper chloride and 49 mg (0.29 mmol) 2-methyl-8-vinyl- quinoline in 17 ml methylene chloride was stirred at 300C for 90 min. The reaction mixture was evaporated to dryness and the isolated crude product purified by silica gel chromatography (hexane / ethyl acetat 7:3) and finally digested in 15 ml hexane at room temperature for 30 min to yield 157 mg (96%) of the title compound as green crystals. MS: 632.9 (M+). 1H-NMR (300 MHz, C6D6): 2.15 (s, 3H); 2.29 (s, 6H); 2.64 (s, 12H); 3.49 (s, 4H); 6.30 (d, J=8.4Hz, IH); 6.80 (t, J=7.3Hz, IH); 6.98 (s, 4H); 7.10 (d, J=8.4Hz, IH); 7.40 (d, J=8.1Hz, IH); 7.52 (d, J=7.0Hz, IH), 17.15-17.32 (br, IH). Anal, calcd. for C32H35N3Cl2Ru: C, 60.66; H, 5.57; N, 6.63; Cl, 11.19. Found: C, 60.33; H, 5.58; N, 6.27; Cl, 10.90.

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Reference£º
Patent; F. HOFFMANN-LA ROCHE AG; WO2008/644; (2008); A1;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

Introduction of a new synthetic route about (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium

With the rapid development of chemical substances, we look forward to future research findings about 246047-72-3

To a solution of 13b (40.0 mg, 0.065 mmol) in anhydrous CH2Cl2 (6.0 ml) was added2nd generation Grubbs catalyst (50.3 mg, 0.059 mmol) and CuCl (I) (13.0 mg, 0.13mmol) under nitrogen at 30 C and stirred for 3 h. The reaction mixture was concentrated in vacuo, and the residue was purified by column chromatography onsilica gel (hexane / AcOEt = 2 / 1) to give 3b (55.5 mg, 78%).green crystals; mp 160-165 C (dec.); 1H NMR (270 MHz, CDCl3) delta 2.01-2.04 (m, 2H),2.22-2.31 (m, 2H), 2.43 (d, J = 14.8 Hz, 18H), 2.77-2.87 (m, 4H), 4.10-4.21 (m, 6H),6.51 (s, 1H), 7.08 (s, 5H), 16.43 (s, 1H); 19F NMR (466 MHz, CDCl3) delta -80.5 (3F),-114.4 (2F), -121.5 (2F), -121.8 (4F), -122.5 (2F), -123.3 (2F), -126.0 (2F); 13C NMR(68 MHz, CDCl3) delta 19.2, 21.0, 22.5, 23.5, 51.7, 69.5, 77.5, 118.9, 124.1, 128.9, 129.5,133.2, 136.3, 138.7, 143.7, 148.5, 210.7, 291.4; IR (FT) 3905, 3857, 3816, 3743, 3700,3642, 3616, 3569, 3013, 2945, 2913, 2856, 2363, 2331, 1738, 1691, 1596, 1555, 1476,1455, 1413, 1245, 1203, 1140, 1108, 1035, 993, 915, 857, 814, 730 cm-1; HRMS (FAB)m/z [M+H]+ calcd for C41H40Cl2F17N2ORu 1072.1290, found 1072.1320.

With the rapid development of chemical substances, we look forward to future research findings about 246047-72-3

New learning discoveries about 246047-72-3

246047-72-3, Example 52 Synthesis of Ru complex 6a To a 50 mL two-necked round bottom flask, after filling with Ar atmosphere, were added ligand 5a (l .Ommol) and CuCl (3.0mmol, 3eq) and 30 mL dry DCM, followed by refilling with Ar three times and protected with Ar balloon in close system. Ru complex lb (l.Ommol) was added under Ar protection, and the mixture was stirred for 0.5 hr at room temperature. After the reaction was complete, the solution was filtered and the filtrate was concentrated and slurred with silica gel. The crude was obtained by silica gel column chromatography and washed with methanol or pentane-DCM to obtain 453mg of yellow-green solid product 6a, yield: 79%. Ru complex (6a) 1HNMR (400 MHz, CDC13): delta 18.53 (s, 1H, Ru=CH), 8.59 (s, 1H), 7.28-6.49 (m, 11H), 4.160 (s, 4H, NCH2CH2N), 2.50 (s, 12H), 2.42 (s, 6H).; Example 59 Synthesis of Ru complex 6h The synthetic procedure is the same as in Example 52 in 1.0 mmol scale. 106 mg of yellow-green solid product 6h was obtained (37% yield). Ru complex (6h) 1HNMR (400 MHz, CDC13): delta 16.52 (s, 1H, Ru=CH), 8.43 (s,1H, N=CH), 8.10 (s, 1H), 7.46-7.22 (m, 2H), 7.73-6.96 (m, 8H), 4.19 (s, 4H, NCH2CH2N), 3.95 (s, 3H), 3.87 (s, 3H), 2.49 (s, 12H), 2.48 (s, 6H).

Reference£º
Patent; ZANNAN SCITECH CO., LTD.; ZHAN, James Zheng-Yun; WO2011/79439; (2011); A1;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI