M.W:800-900| Page 131 of 132 | Ruthenium catalysts

New learning discoveries about 246047-72-3

246047-72-3, 246047-72-3 (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium 11147261, aruthenium-catalysts compound, is more and more widely used in various fields.

246047-72-3, (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium is a ruthenium-catalysts compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

To a solution of 18 (10.5 g, 22.4 mmol) in THF (120 mL) was added TBAF (1.0 mol/L in THF, 90 mL, 90 mmol) at 20 C, and the mixture was stirred for 5 h. Then, the mixture was concentrated under reduced pressure, and the residue was purified by recrystallization (PhH + H2O) to give 19 (7.50 g, 21.2 mmol, 95%) as a colorless needle. 19: mp 217e219 C; [a]D24 39.7 (c 0.0350, CHCl3); IR (KBr) n 3484, 3054, 3026, 2891, 1436, 1380, 1265, 1103, 1031, 861, 828, 801, 744, 678, 549, 476 cm1; 1H NMR (400 MHz, CDCl3) d 2.36e2.45 (1H, m), 2.66 (1H, ddd, J 3.6, 8.3, 15.9 Hz), 2.80 (1H, s), 3.34 (1H, t, J 8.5 Hz), 3.39 (1H, ddd, J 4.0, 9.7, 19.4 Hz), 3.53 (1H, dt, J 5.2, 9.7 Hz), 3.65 (1H, t, J 9.3 Hz), 3.77 (1H, t, J 10.5 Hz), 3.89 (1H, t, J 8.8 Hz), 4.07 (1H, brqd, J 2.9, 15.3 Hz), 4.35e4.40 (2H, m), 5.73(1H, s), 5.82e5.88 (1H, m), 5.92e5.98 (1H, m), 7.46e7.50 (2H, m), 7.62 (1H, d, J 8.5 Hz), 7.82e7.88 (3H, m), 7.99 (1H, s); 13C NMR (100 MHz, CDCl3) d 34.3 (CH2), 68.5 (CH2), 68.9 (CH2), 69.9 (CH), 73.6 (CH), 76.4 (CH), 80.9 (CH), 87.8 (CH), 101.9 (CH), 123.8 (CH), 125.8 (CH), 126.1 (CH), 126.4 (CH), 127.3 (CH), 127.7 (CH), 128.2 (CH),128.4 (CH), 131.7 (CH), 132.9 (C), 133.7 (C), 134.4 (C); EI-HRMS (m/z) calcd for C21H22O5 [M]: 354.1467, found: 354.1464.

Reference£º
Article; Sato, Takuto; Nogoshi, Keisuke; Goto, Akiyoshi; Domon, Daisuke; Kawamura, Natsumi; Nomura, Yoshitaka; Sato, Daisuke; Tanaka, Hideki; Murai, Akio; Katoono, Ryo; Kawai, Hidetoshi; Suzuki, Takanori; Fujiwara, Kenshu; Kondo, Yoshihiko; Akiba, Uichi; Tetrahedron; vol. 73; 6; (2017); p. 703 – 726;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

Application of 1,3-Bis(2,6-diisopropylphenyl)imidazolium chloride

As the rapid development of chemical substances, we look forward to future research findings about 246047-72-3

A common heterocyclic compound, the ruthenium-catalysts compound, name is (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium,cas is 246047-72-3, mainly used in chemical industry, its synthesis route is as follows.,246047-72-3

A suspension of 1.00 g (1.18 mmol) of [RuCl2(PCy3)(ImH2Mes)(phenylmethylene)](commercially available from Sigma- Aldrich Inc., St. Louis, USA), 0.13 g (1.30 mmol) of copper chloride and 0.38 g (1.30 mmol) oflambda/-phenyl-2-[((E,Z)-2-propenyl)-phenoxy]- propionamide as a 4:1 mixture ofE/Z-isomers in 75 ml of dichloromethane was stirred for 30 min at 400C. The reaction mixture was evaporated to dryness at 400C/ 10 mbar. The residue was stirred in 75 ml of ethyl acetate for 30 min at room temperature. The dark green suspension was filtered and the filtrate was evaporated to dryness at 40C/10 mbar. The crude title product was purified by silica gel chromatography (cyclohexane/ethyl acetate 4:1) to yield 0.75 g (88% yield) of the title compound as a green powder.MS: 731.1 (M+). Anal, calcd. for C37H4ICl2N3O2Ru ? V3 C6Hi2: C, 61.65; H, 5.97; N, 5.53; Cl, 9.33. Found: C, 61.83; H, 6.71; N, 5.35; Cl, 8.93.

As the rapid development of chemical substances, we look forward to future research findings about 246047-72-3

Reference£º
Patent; F. HOFFMANN-LA ROCHE AG; WO2009/124853; (2009); A1;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

Some tips on 246047-72-3

246047-72-3, The synthetic route of 246047-72-3 has been constantly updated, and we look forward to future research findings.

Grubbs second generation catalyst (100 mg, 0.117 mmol), 2-[(2,4,6-trimethylphenylimino)methyl]phenol (pKa: 8.84+/-0.30) (0.117 mmol), silver (I) carbonate (16.27 mg, 0.058 mmol), and THF (2 ml) were reacted at room temperature during 2 h. The solvent was evaporated and crude reaction product purified on chromatography column to give an orange-brown complex. Yield 30%.

246047-72-3, The synthetic route of 246047-72-3 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; Telene S.A.S.; US2011/137043; (2011); A1;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

Application of Thiomorpholine 1,1-dioxide

As the rapid development of chemical substances, we look forward to future research findings about 246047-72-3

The ruthenium-catalysts compound, name is (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium,cas is 246047-72-3, mainly used in chemical industry, its synthesis route is as follows.,246047-72-3

Grubbs second generation catalyst (100 mg, 0.118 mmol) andacrylonitrile (25 mg, 0.472 mmol) were stirred in toluene (5 mL) for15 h at room temperature. After removal of volatiles by evacuation,the brown powder was washed with pentane (3 ¡Á 5 mL) and driedunder vacuum, affording 7-CN as a brown solid in a 80% yield

As the rapid development of chemical substances, we look forward to future research findings about 246047-72-3

Reference£º
Article; Vancompernolle, Tom; Vignon, Paul; Trivelli, Xavier; Mortreux, Andre; Gauvin, Regis M.; Catalysis Communications; vol. 77; (2016); p. 75 – 78;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

New learning discoveries about 246047-72-3

246047-72-3 (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium 11147261, aruthenium-catalysts compound, is more and more widely used in various fields.

To a suspension of copper(I) chloride (13 mg, 0.12 mmol) and tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidene][benzylidene]ruthenium(IV) dichloride (102 mg; 0.12 mmol) in 2 ml of dichloromethane was added a solution of the appropriate styrene derivative (0.132 mmol) dissolved in 3 ml of dichloromethane. After stirring at 40 C. for 20 min, the reaction solution was concentrated under reduced pressure. The residue was taken up in 20 ml of ethyl acetate and filtered through a Pasteur pipette with silica gel. The filtrate was concentrated again under reduced pressure and the residue was washed with a very small amount of ethyl acetate and cold pentane., 246047-72-3

Reference£º
Patent; Kadyrov, Renat; Szadkowska, Anna; Grela, Karol; Barbasiewicz, Michal; US2008/275247; (2008); A1;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

Application of 5-Bromobenzo[d]oxazole

As the rapid development of chemical substances, we look forward to future research findings about 246047-72-3

Grubbs second generation catalyst (100 mg, 0.117 mmol), 2-[(2,4,6-trimethylphenylimino)methyl]phenol (pKa: 8.84+/- 0.30) (0.117 mmol), silver (I) carbonate (16.27 mg, 0.058 mmol), and THF (2 ml) were reacted at room temperature during 2 h. The solvent was evaporated and crude reaction product purified on chromatography column to give an orange-brown complex. Yield 30%.

As the rapid development of chemical substances, we look forward to future research findings about 246047-72-3

Reference£º
Patent; Telene SAS; EP2151446; (2010); A1;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

Analyzing the synthesis route of 246047-72-3

As the paragraph descriping shows that 246047-72-3 is playing an increasingly important role.

Complex 1(2.0 grams) was dissolved in toluene (10 mL), and 4-phenylpyridine (1.50 grams, 4 mol equivalents) was added. The reaction flask was purged with argon and the reaction mixture was stirred for approximately 12 hours at about 20 C. to about 25 C. during which time a color change from dark purple to dark green was observed. The reaction mixture was transferred into 75 mL of cold (about 0 C.) pentane, and a dark green solid precipitated. The precipitate was filtered, washed with 4¡Á20 mL of cold pentane, and dried under vacuum to afford (IMesH2)(C11H9N)2(Cl)2RuCHPh 13 as a dark green powder (2.0 grams, 97% yield). 1H NMR (500 MHz, CD2Cl2): delta19.23 (s, 1H, CHPh), 8.74 (br. s, 2H, pyridine), 7.91 (br. s, 2H, pyridine), 7.70-7.08 (multiple peaks, 19H, ortho CH, para CH, meta CH, pyridine), 6.93 (br. S, 2H, Mes CH) 6.79 (br. s, 2H, Mes CH), 4.05 (br. s, 4H, NCH2CH2N), 2.62-2.29 (multiple peaks, 18H, Mes CH3).

As the paragraph descriping shows that 246047-72-3 is playing an increasingly important role.

Reference£º
Patent; Grubbs, Robert H.; Morgan, John P.; Love, Jennifer A.; Trnka, Tina M.; US2003/236427; (2003); A1;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

Downstream synthetic route of 246047-72-3

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.246047-72-3,(1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium,as a common compound, the synthetic route is as follows.

After a 50 mL two-necked flask was purged with argon, the ligand 3 cp (10 mmol), CuCl (30 mmol, 3 eq) and 30 mL of dry DCM were sequentially added and the mixture was purged three times with argon to protect the closed system with an argon balloon. Ruthenium complex 1b (12 mmol) was added under argon atmosphere, and the reaction was carried out at room temperature for 0.5 hour. After completion of the reaction, silica gel was added to the filtrate after filtration, and the crude product was obtained by silica gel column chromatography, and then washed with methanol or pentane-DCM to obtain a green solid product 4cp, yield: 68%.

Reference£º
Patent; Zannan Science And Technology (Shanghai) Co., Ltd.; Zhan Zhengyun; (102 pag.)CN104262403; (2017); B;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

Analyzing the synthesis route of 246047-72-3

As the paragraph descriping shows that 246047-72-3 is playing an increasingly important role.

After a 50 mL two-necked flask was purged with argon, a ligand 7b (10 mmol), CuCl (30 mmol, 3 eq) and 30 mL of dry DCM were sequentially added and the mixture was purged three times with argon to protect the closed system with an argon balloon. Ruthenium complex 1b (12 mmol) was added under argon atmosphere, and the reaction was carried out at room temperature for 0.5 hour. After the reaction was over, silica gel was added to the filtrate to produce sand. The crude product was obtained by silica gel column chromatography and then washed with methanol or pentane-DCM to obtain a green solid product 8b in a yield of 79%., 246047-72-3

As the paragraph descriping shows that 246047-72-3 is playing an increasingly important role.

Brief introduction of 246047-72-3

As the paragraph descriping shows that 246047-72-3 is playing an increasingly important role.

Grubbs second generation catalyst (100 mg, 0.117 mmol), 2-[(2,4,6-trimethylphenylimino)methyl]phenol (pKa: 8.84+/- 0.30) (0.117 mmol), silver (I) carbonate (16.27 mg, 0.058 mmol), and THF (2 ml) were reacted at room temperature during 2 h. The solvent was evaporated and crude reaction product purified on chromatography column to give an orange-brown complex. Yield 30%., 246047-72-3

As the paragraph descriping shows that 246047-72-3 is playing an increasingly important role.

Reference£º
Patent; Telene SAS; EP2151446; (2010); A1;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI