50982-12-2, Dichloro(cycloocta-1,5-diene)ruthenium(II) is a ruthenium-catalysts compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
The catalyst precursor, preferably [RuCI2(COD)]m (1 eq.) (COD = cis,cis-cycloocta-1 ,5 diene), 1 ,4-bis(diphenylphosphino)butane (1.0-1 .2 eq., preferably 1.0 eq.) and 2-picolylamine (1 .0-1.4 eq., preferably 1.225 eq.) were dissolved in one of the above mentioned solvents, preferably methyl isobutylketone (10-20 ml/g Ru-precursor, preferably 20 ml/g). The mixture was heated to reflux for 3 – 5 hours and then cooled to ambient temperature. The solid precipitate was filtered off and washed with the same solvent that was used for the reaction. A person skilled in the art can determine the cis-/trans- isomeric ratio by NMR. The diastereomeric ratios generated by this method are usually in the range of d.r. (diastereomeric ratio) >98% towards the cis isomer. The same results can be achieved starting with [RuCI2(dmso-KS)3(dmso-KO)], [RuCI2(dmso-KS)4]or [RuCI2(bicyclo[2.2.1 ]hepta- 2,5-diene)]m as precursor
As the paragraph descriping shows that 50982-12-2 is playing an increasingly important role.
Reference£º
Patent; SYNGENTA PARTICIPATIONS AG; LOTHSCHUETZ, Christian; SAINT-DIZIER, Alexandre Christian; WO2014/166777; (2014); A1;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI