Tag: 203714-71-0

Name is Dichloro(2-isopropoxyphenylmethylene)(tricyclohexylphosphine)ruthenium (II), as a common heterocyclic compound, it belongs to ruthenium-catalysts compound, and cas is 203714-71-0, its synthesis route is as follows.,203714-71-0

PIB-supported Grubbs-Hoveyda 2nd generation catalyst (molecule 8): A mixture of 1.14 g (0.48 mmol) of 1,3-bis(2,6-dimethyl-4-(polyisobutyl)phenyl)-4,5-dihydro-imidazolium tetrafluoroborate, 0.15 g (0.75 mmol) of KHMDS, 0.05 g (0.5 mmol) of CuCl and 0.36 g (0.57 mmol) of 1st generation Hoveyda-Grubbs catalyst was prepared was dissolved in 5 mL of toluene. The solution was heated to 100 C. for 3 hours. Solvent was removed under reduced pressure and purified by column chromatography (dichloromethane) resulting in a dark green viscous residue. The yield was 60% (0.75 g). 1H-NMR (500 MHz, CDCl3), delta: 0.8-1.6 (m, 280H), 1.87 (s, 2H), 2.41 (b, 6H), 2.62 (b, 6H) 4.15 (s, 4H), 4.90 (m, 1H) 6.8 (m, 2H), 6.98 (m, 1H), 7.22 (b, 4H), 7.47 (m, 1H), and 16.67 (s, 1H). 13C NMR (125 MHz, CDCl3), delta: 21.62, multiple peaks between 30-40 and 58-60, 113.10, 122.42, 123.09, 126.53, 127.01, 129.69, 137.30, 139.21, 145.41, 145.44, 152.16, 152.43, 152.45, 211.19, and 297.23 (m).

With the complex challenges of chemical substances, we look forward to future research findings about Dichloro(2-isopropoxyphenylmethylene)(tricyclohexylphosphine)ruthenium (II)

Reference£º
Patent; Bergbreiter, David E.; Bazzi, Hassan S.; Hongfa, Chayanant; US2009/203860; (2009); A1;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

Name is Dichloro(2-isopropoxyphenylmethylene)(tricyclohexylphosphine)ruthenium (II), as a common heterocyclic compound, it belongs to ruthenium-catalysts compound, and cas is 203714-71-0, its synthesis route is as follows.,203714-71-0

NHC ligand precursor 10 (156 mg, .3 mmol), KOz-Bu(F g) (66 mg, .3 mmol), and ruthenium complex 11 (132 mg, .22 mmol) were all combined in toluene in a glove box. The flask was removed and stirred at 60 0C for 18 hours in a fume hood. The reaction mixture was then directly purified by flash column chromatography (5% Et2theta/Hexanes, run 2 times) to yield catalyst 12 (34 mg, 20%) as a green oil. The catalyst was then lyophilized from benzene to give a pale green solid. It should be noted that by 1H NMR the conversion to 12 is 50%. 1H NMR (300 MHz, CDCl3) delta 16.91 (IH, s), 8.14-8.13 (2H, m), 7.73 (2H, m), 7.64 (IH, m), 7.52 (IH, m), 7.06-6.92 (2H, m), 6.62 (IH, t, J = 7.5 Hz), 6.31 (IH, d, J – 8.4 Hz), 4.47 (IH, quint, J = 6 Hz), 3.51 (4H, s), 1.51 (18H, s), 1.35 (6H, d, J = 6 Hz), 1.24 (18H, s); HRMS (EI+) calc for C4IH58N2OCl2Ru 766.2970. Found 766.3007. Fig. 4 depicts the single crystal X-ray structure was obtained for catalyst 12.

With the complex challenges of chemical substances, we look forward to future research findings about Dichloro(2-isopropoxyphenylmethylene)(tricyclohexylphosphine)ruthenium (II)

Reference£º
Patent; MATERIA, INC.; CALIFORNIA INSTITUTE OF TECHNOLOGY; WO2007/75427; (2007); A1;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.203714-71-0,Dichloro(2-isopropoxyphenylmethylene)(tricyclohexylphosphine)ruthenium (II),as a common compound, the synthetic route is as follows.,203714-71-0

A dry, 1000-mL, one-necked, round-bottomed flask is equipped with a magnetic stirring bar, rubber septum and an argon inlet. The flask is charged under an argon atmosphere with a solid SIMES x HBF4 2 (35.28 mmol, 13.9 g) and dry n-hexane (400 ml_). A solution of potassium tert-amylate (21.6 ml_, 36.75 mmol) is added from a syringe and the resulting mixture is stirred under argon at room temperature for 1 h. To the resulted solution a solid Hoveyda-Grubbs 1st generation catalyst 1 (29.4 mmol, 17.6 g) is added in one portion. The flask is equipped with a reflux condenser with an argon inlet at the top and the reaction mixture is refluxed for 2 h. The contents of the flask are cooled to room temperature and solid CuCI (51.45 mmol, 5.1 g) is added slowly in three portions and the resulting mixture is refluxed for 2 h. From this point forth, all manipulations are carried out in air.; 1.11. Isolation of the product by crystallization; The reaction mixture is evaporated to dryness and re-dissolved in ethyl acetate (200 ml_). The solution is filtrated through a Buchner funnel with glass frit filled with Celite and then concentrated in vacuo. The residue is dissolved in ambient temp. 1 :10 v/v mixture of CH2CI2 and methanol (220 ml_). After concentration to ca. % of the initial volume using a rotary evaporator (room temperature) crystals are precipitated. These crystals are filtered- off on a Buchner funnel with glass frit. The crystals are washed twice with small portions of CH3OH (-20 ml_), and dried in vacuo to give pure Hoveyda 2nd catalysts 3 (25.3 mmol, 15.81 g). The filtrate after crystallization is evaporated to dryness and crystallized for the second time from CH2CI2 and methanol using the same protocol giving an additional crop of pure Hoveyda 2nd generation catalyst (1.7 mmol, 1.08 g). The total yield of pure Hoveyda-Grubbs 2nd generation catalyst 3 is 92% (27.0 mmol, 16.9 g).

203714-71-0 Dichloro(2-isopropoxyphenylmethylene)(tricyclohexylphosphine)ruthenium (II) 10941020, aruthenium-catalysts compound, is more and more widely used in various.

Reference£º
Patent; BOEHRINGER INGELHEIM INTERNATIONAL GMBH; BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG; WO2007/54483; (2007); A1;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

As a common heterocyclic compound, it belongs to quinuclidine compound,Quinuclidine-4-carboxylic acid hydrochloride,40117-63-3,Molecular formula: C8H14ClNO91,mainly used in chemical industry, its synthesis route is as follows.,203714-71-0

In a glove box, NHC ligand precursor 23 (63 mg, .13, mmol), ruthenium precursor 11 (78 mg, .13 mmol) and KOMJu(Fe) (29 mg, .13 mmol) were combined in toluene. The flask was sealed, removed from the glove box and stirred at 60 0C for 18 hours. The reaction was concentrated and purified by flash column chromatography (5% –> 20% Et2O/Pent). There were 3 bands that could be isolated from this column, first 2 brown bands and then one green band. The second brown band was the desired product; however, it was not completely pure after one column. Recolumning in 10% Et2O/Pentane gave a brown oil product completely pure by 1H NMR (9 mg, 9%) and another fraction still slightly impure (18 mg, 18%). The products were lyophilized from benzene to give solids. 1H NMR (300 MHz, CDCl3) delta 16.78 (s, IH), 8.13 (br, 2H), 7.74-7.62 (m, 4H), 7.07-7.04 (m, IH), 6.97 (dd, J = 3, 1.5 Hz, IH), 6.66 (t, J = 7.5 Hz, 3H), 6.34 (d, J = 8.4 Hz, IH), 4.49 (sept, J = 6 Hz, IH), 1..44 (d, J = 6 Hz, 6H), 1.44 (br, 18H), 1.18 (br, 18H); 13C (75 MHz, CDCl3) delta; HRMS (EI+) calc for C4IH56Cl2N2ORu, 764.2814. Found 764.2842.

With the complex challenges of chemical substances, we look forward to future research findings about Dichloro(2-isopropoxyphenylmethylene)(tricyclohexylphosphine)ruthenium (II),belong ruthenium-catalysts compound

Reference£º
Patent; MATERIA, INC.; CALIFORNIA INSTITUTE OF TECHNOLOGY; WO2007/75427; (2007); A1;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

As a common heterocyclic compound, it belongs to ruthenium-catalysts compound, name is Dichloro(2-isopropoxyphenylmethylene)(tricyclohexylphosphine)ruthenium (II), and cas is 203714-71-0, its synthesis route is as follows.,203714-71-0

NHC ligand precursor 21 (9 mg, .03 mmol), KOz-Bu(F6) (6 mg, .03 mmol), and ruthenium complex 911 (13 mg, .02 mmol) were all combined in CgDbeta in a screw cap NMR tube in a glove box. The NMR tube was removed and heated at 600C for 2.5 hour in a fume hood. Conversion to catalyst 22 was determined to be 14% by proton NMR. 1H NMR (300 MHz, CDCl3) delta 17.19 (IH, s).

With the complex challenges of chemical substances, we look forward to future research findings about Dichloro(2-isopropoxyphenylmethylene)(tricyclohexylphosphine)ruthenium (II)

Reference£º
Patent; MATERIA, INC.; CALIFORNIA INSTITUTE OF TECHNOLOGY; WO2007/75427; (2007); A1;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

203714-71-0, Dichloro(2-isopropoxyphenylmethylene)(tricyclohexylphosphine)ruthenium (II) is a ruthenium-catalysts compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

PIB-supported Grubbs-Hoveyda 2nd generation catalyst (molecule 8): A mixture of 1.14 g (0.48 mmol) of 1,3-bis(2,6-dimethyl-4-(polyisobutyl)phenyl)-4,5-dihydro-imidazolium tetrafluoroborate, 0.15 g (0.75 mmol) of KHMDS, 0.05 g (0.5 mmol) of CuCl and 0.36 g (0.57 mmol) of 1st generation Hoveyda-Grubbs catalyst was prepared was dissolved in 5 mL of toluene. The solution was heated to 100 C. for 3 hours. Solvent was removed under reduced pressure and purified by column chromatography (dichloromethane) resulting in a dark green viscous residue. The yield was 60% (0.75 g). 1H-NMR (500 MHz, CDCl3), delta: 0.8-1.6 (m, 280H), 1.87 (s, 2H), 2.41 (b, 6H), 2.62 (b, 6H) 4.15 (s, 4H), 4.90 (m, 1H) 6.8 (m, 2H), 6.98 (m, 1H), 7.22 (b, 4H), 7.47 (m, 1H), and 16.67 (s, 1H). 13C NMR (125 MHz, CDCl3), delta: 21.62, multiple peaks between 30-40 and 58-60, 113.10, 122.42, 123.09, 126.53, 127.01, 129.69, 137.30, 139.21, 145.41, 145.44, 152.16, 152.43, 152.45, 211.19, and 297.23 (m).

As the paragraph descriping shows that 203714-71-0 is playing an increasingly important role.

Reference£º
Patent; Bergbreiter, David E.; Bazzi, Hassan S.; Hongfa, Chayanant; US2009/203860; (2009); A1;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.203714-71-0,Dichloro(2-isopropoxyphenylmethylene)(tricyclohexylphosphine)ruthenium (II),as a common compound, the synthetic route is as follows.

In a glove box, NHC ligand precursor 23 (63 mg, .13, mmol), ruthenium precursor 11 (78 mg, .13 mmol) and KOMJu(Fe) (29 mg, .13 mmol) were combined in toluene. The flask was sealed, removed from the glove box and stirred at 60 0C for 18 hours. The reaction was concentrated and purified by flash column chromatography (5% –> 20% Et2O/Pent). There were 3 bands that could be isolated from this column, first 2 brown bands and then one green band. The second brown band was the desired product; however, it was not completely pure after one column. Recolumning in 10% Et2O/Pentane gave a brown oil product completely pure by 1H NMR (9 mg, 9%) and another fraction still slightly impure (18 mg, 18%). The products were lyophilized from benzene to give solids. 1H NMR (300 MHz, CDCl3) delta 16.78 (s, IH), 8.13 (br, 2H), 7.74-7.62 (m, 4H), 7.07-7.04 (m, IH), 6.97 (dd, J = 3, 1.5 Hz, IH), 6.66 (t, J = 7.5 Hz, 3H), 6.34 (d, J = 8.4 Hz, IH), 4.49 (sept, J = 6 Hz, IH), 1..44 (d, J = 6 Hz, 6H), 1.44 (br, 18H), 1.18 (br, 18H); 13C (75 MHz, CDCl3) delta; HRMS (EI+) calc for C4IH56Cl2N2ORu, 764.2814. Found 764.2842.

As the paragraph descriping shows that 203714-71-0 is playing an increasingly important role.

Reference£º
Patent; MATERIA, INC.; CALIFORNIA INSTITUTE OF TECHNOLOGY; WO2007/75427; (2007); A1;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

Dichloro(2-isopropoxyphenylmethylene)(tricyclohexylphosphine)ruthenium (II), cas is 203714-71-0, it is a common heterocyclic compound, the ruthenium-catalysts compound, its synthesis route is as follows.

A dry, 1000-mL, one-necked, round-bottomed flask is equipped with a magnetic stirring bar, rubber septum and an argon inlet. The flask is charged under an argon atmosphere with a solid SIMES x HBF4 2 (35.28 mmol, 13.9 g) and dry n-hexane (400 ml_). A solution of potassium tert-amylate (21.6 ml_, 36.75 mmol) is added from a syringe and the resulting mixture is stirred under argon at room temperature for 1 h. To the resulted solution a solid Hoveyda-Grubbs 1st generation catalyst 1 (29.4 mmol, 17.6 g) is added in one portion. The flask is equipped with a reflux condenser with an argon inlet at the top and the reaction mixture is refluxed for 2 h. The contents of the flask are cooled to room temperature and solid CuCI (51.45 mmol, 5.1 g) is added slowly in three portions and the resulting mixture is refluxed for 2 h. From this point forth, all manipulations are carried out in air.; 1.11. Isolation of the product by crystallization; The reaction mixture is evaporated to dryness and re-dissolved in ethyl acetate (200 ml_). The solution is filtrated through a Buchner funnel with glass frit filled with Celite and then concentrated in vacuo. The residue is dissolved in ambient temp. 1 :10 v/v mixture of CH2CI2 and methanol (220 ml_). After concentration to ca. % of the initial volume using a rotary evaporator (room temperature) crystals are precipitated. These crystals are filtered- off on a Buchner funnel with glass frit. The crystals are washed twice with small portions of CH3OH (-20 ml_), and dried in vacuo to give pure Hoveyda 2nd catalysts 3 (25.3 mmol, 15.81 g). The filtrate after crystallization is evaporated to dryness and crystallized for the second time from CH2CI2 and methanol using the same protocol giving an additional crop of pure Hoveyda 2nd generation catalyst (1.7 mmol, 1.08 g). The total yield of pure Hoveyda-Grubbs 2nd generation catalyst 3 is 92% (27.0 mmol, 16.9 g).

With the rapid development of chemical substances, we look forward to future research findings about 203714-71-0

Reference£º
Patent; BOEHRINGER INGELHEIM INTERNATIONAL GMBH; BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG; WO2007/54483; (2007); A1;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

203714-71-0, Dichloro(2-isopropoxyphenylmethylene)(tricyclohexylphosphine)ruthenium (II) is a ruthenium-catalysts compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

NHC ligand precursor 21 (9 mg, .03 mmol), KOz-Bu(F6) (6 mg, .03 mmol), and ruthenium complex 911 (13 mg, .02 mmol) were all combined in CgDbeta in a screw cap NMR tube in a glove box. The NMR tube was removed and heated at 600C for 2.5 hour in a fume hood. Conversion to catalyst 22 was determined to be 14% by proton NMR. 1H NMR (300 MHz, CDCl3) delta 17.19 (IH, s).

203714-71-0 Dichloro(2-isopropoxyphenylmethylene)(tricyclohexylphosphine)ruthenium (II) 10941020, aruthenium-catalysts compound, is more and more widely used in various.

Reference£º
Patent; MATERIA, INC.; CALIFORNIA INSTITUTE OF TECHNOLOGY; WO2007/75427; (2007); A1;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.203714-71-0,Dichloro(2-isopropoxyphenylmethylene)(tricyclohexylphosphine)ruthenium (II),as a common compound, the synthetic route is as follows.

NHC ligand precursor 10 (156 mg, .3 mmol), KOz-Bu(F g) (66 mg, .3 mmol), and ruthenium complex 11 (132 mg, .22 mmol) were all combined in toluene in a glove box. The flask was removed and stirred at 60 0C for 18 hours in a fume hood. The reaction mixture was then directly purified by flash column chromatography (5% Et2theta/Hexanes, run 2 times) to yield catalyst 12 (34 mg, 20%) as a green oil. The catalyst was then lyophilized from benzene to give a pale green solid. It should be noted that by 1H NMR the conversion to 12 is 50%. 1H NMR (300 MHz, CDCl3) delta 16.91 (IH, s), 8.14-8.13 (2H, m), 7.73 (2H, m), 7.64 (IH, m), 7.52 (IH, m), 7.06-6.92 (2H, m), 6.62 (IH, t, J = 7.5 Hz), 6.31 (IH, d, J – 8.4 Hz), 4.47 (IH, quint, J = 6 Hz), 3.51 (4H, s), 1.51 (18H, s), 1.35 (6H, d, J = 6 Hz), 1.24 (18H, s); HRMS (EI+) calc for C4IH58N2OCl2Ru 766.2970. Found 766.3007. Fig. 4 depicts the single crystal X-ray structure was obtained for catalyst 12.

The synthetic route of 203714-71-0 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; MATERIA, INC.; CALIFORNIA INSTITUTE OF TECHNOLOGY; WO2007/75427; (2007); A1;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI