50982-12-2| Page 8 of 8 | Ruthenium catalysts

Simple exploration of 50982-12-2

The synthetic route of 50982-12-2 has been constantly updated, and we look forward to future research findings.

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.50982-12-2,Dichloro(cycloocta-1,5-diene)ruthenium(II),as a common compound, the synthetic route is as follows.

The catalyst precursor, preferably [RuCI2(COD)]m (1 eq.), 1 ,4-bis(diphenylphosphino)butane (1 .0-1 .2 eq., preferably 1 .0 eq.) and 2- quinolinylmethylamine (1.0-1 .4 eq., preferably 1.225 eq.) were dissolved in one of the above mentioned solvents, preferably cyclohexanone (10- 20 ml/g Ru-precursor, preferably 20 ml/g). The mixture was heated at 130 C for 1 hour and then cooled to ambient temperature. The solid precipitate was filtered off and washed with the same solvent that was used for the reaction. A person skilled in the art can determine the cis-/trans- isomeric ratio by NMR. The diastereomeric ratios generated by this method are usually in the range of d.r. (diastereomeric ratio) >98% towards the cis isomer. The same results can be achieved starting with [RuCI2(dmso-KS)3(dmso-KO)], [RuCI2(dmso-KS)4]or [RuCI2(bicyclo[2.2.1]hepta-2,5-diene)]m as precursor

The synthetic route of 50982-12-2 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; SYNGENTA PARTICIPATIONS AG; LOTHSCHUETZ, Christian; SAINT-DIZIER, Alexandre Christian; WO2014/166777; (2014); A1;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

Brief introduction of 50982-12-2

As the paragraph descriping shows that 50982-12-2 is playing an increasingly important role.

Separately, 200 ml of well dried tetrahydrofuran was fed to a 500 ml flask whose inside had been substituted by argon, and 5 g of dichloro(cyclooctadienyl)ruthenium was injected into the flask and well mixed with the above tetrahydrofuran to obtain a suspension. This suspension was cooled to -78 C. in a stream of argon, and 15 ml of the above synthesized tetrahydrofuran solution of trifluoromethyl cyclopentadienyl sodium was added dropwise to the suspension over 1 hour. The reaction mixture was further stirred at -78 C. for 3 hours and returned to room temperature under agitation over 12 hours. After the reaction mixture was let pass through a neutral alumina column in a stream of argon to be purified and concentrated, it was purified again by a neutral alumina column to obtain 0.2 g of bis(trifluoromethylcyclopentadienyl)ruthenium (yield rate of 30%).

As the paragraph descriping shows that 50982-12-2 is playing an increasingly important role.

Reference£º
Patent; JSR Corporation; US2006/240190; (2006); A1;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

Some tips on 50982-12-2

The synthetic route of 50982-12-2 has been constantly updated, and we look forward to future research findings.

50982-12-2, Dichloro(cycloocta-1,5-diene)ruthenium(II) is a ruthenium-catalysts compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: The following common procedure was followed for the synthesesof complexes 1-5: A mixture of the ligand (0.36 mmol) and Ru(1,5-cod)Cl2(0.36 mmol) was dissolved in dry ethanol (10 ml) and the resultingmixture was refluxed for 2 h. The reaction volume was concentratedto a third of its original volume and the suspension was keptat 4 C overnight to give brick red solid which was filtered off,washed with cold ethanol and then diethyl ether. The solid wasdissolved in chloroform and excess of n-hexane was added toinduce the precipitation of the brick red solid product.

The synthetic route of 50982-12-2 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Thangavel, Saravanan; Rajamanikandan, Ramar; Friedrich, Holger B.; Ilanchelian, Malaichamy; Omondi, Bernard; Polyhedron; vol. 107; (2016); p. 124 – 135;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

Downstream synthetic route of 50982-12-2

50982-12-2 Dichloro(cycloocta-1,5-diene)ruthenium(II) 11000435, aruthenium-catalysts compound, is more and more widely used in various.

b) A brown suspension of RuCl2(1,5-cyclooctadiene) (560 mg; 2 mmol), 0.6 ml of 1,8-diazobicyclo[5.4.0]undec-7-ene (DBU) and 1.18 g of tricyclohexylphosphine in 60 ml of isopropanol was stirred at 80 C. for 2 hours. 60 ml of toluene was added to the resulting brick-red suspension and the mixture was stirred at 80 C. for a further 90 minutes and cooled to -10 C. After addition of 0.55 ml of trimethylsilylacetylene, 10 ml of 2 M HCl solution in diethyl ether were added and the mixture was subsequently stirred for 5 minutes. The mixture was warmed while stirring to 0 C. and stirred for 45 minutes. After evaporation at 0 C. in a high vacuum, the residue was stirred with cold MeOH. The resulting violet powder was washed with cold methanol and dried under reduced pressure. Yield 1.40 g (92%).

50982-12-2 Dichloro(cycloocta-1,5-diene)ruthenium(II) 11000435, aruthenium-catalysts compound, is more and more widely used in various.

Reference£º
Patent; Evonik Degussa GmbH; US2011/40099; (2011); A1;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

Analyzing the synthesis route of 50982-12-2

As the paragraph descriping shows that 50982-12-2 is playing an increasingly important role.

50982-12-2, Dichloro(cycloocta-1,5-diene)ruthenium(II) is a ruthenium-catalysts compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

Example 2; Synthesis of the Alkylidene Complex (2): Ru(cod)Cl2 (660 mg, 2.35 mmol) was suspended in iPrOH (20 ml) under an Ar atmosphere. DBU (0.75 ml) and PCy3 solution (c=20%, 0.77 M in toluene, 7.7 ml) was added. The brown suspension obtained was stirred at 80 C. for 1 hour and toluene (25 ml) was then added. The mixture was stirred at 80 C. for a further 30 minutes. The reaction mixture was then cooled to 0 C. and 1-trimethylsilyl-1-hexyne (2.1 g) was added. After stirring for 10 minutes, HCl solution (c=2 M in Et2O, 2.4 ml) was added to the reaction mixture at 0 C. After stirring for 1 hour, the reaction mixture was evaporated. MeOH (about 30 ml) was added to the residue. Filtration gave the complex 2. The NMR also shows by-products.NMR in CDCl3 delta 31P 35.81 ppm. 1H delta 20.01 ppm.

As the paragraph descriping shows that 50982-12-2 is playing an increasingly important role.

Analyzing the synthesis route of 50982-12-2

As the paragraph descriping shows that 50982-12-2 is playing an increasingly important role.

50982-12-2, Dichloro(cycloocta-1,5-diene)ruthenium(II) is a ruthenium-catalysts compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

The catalyst precursor, preferably [RuCI2(COD)]m (1 eq.) (COD = cis,cis-cycloocta-1 ,5 diene), 1 ,4-bis(diphenylphosphino)butane (1.0-1 .2 eq., preferably 1.0 eq.) and 2-picolylamine (1 .0-1.4 eq., preferably 1.225 eq.) were dissolved in one of the above mentioned solvents, preferably methyl isobutylketone (10-20 ml/g Ru-precursor, preferably 20 ml/g). The mixture was heated to reflux for 3 – 5 hours and then cooled to ambient temperature. The solid precipitate was filtered off and washed with the same solvent that was used for the reaction. A person skilled in the art can determine the cis-/trans- isomeric ratio by NMR. The diastereomeric ratios generated by this method are usually in the range of d.r. (diastereomeric ratio) >98% towards the cis isomer. The same results can be achieved starting with [RuCI2(dmso-KS)3(dmso-KO)], [RuCI2(dmso-KS)4]or [RuCI2(bicyclo[2.2.1 ]hepta- 2,5-diene)]m as precursor

As the paragraph descriping shows that 50982-12-2 is playing an increasingly important role.