Category: 246047-72-3

246047-72-3, (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium is a ruthenium-catalysts compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

After a 50 mL two-necked flask was replaced by argon, the ligand 3cr (10 mmol), CuCl (30 mmol, 3 eq) and 30 mL of dry DCM were sequentially added and the mixture was purged three times with argon to protect the closed system with an argon balloon. Ruthenium complex 1b (12 mmol) was added under argon atmosphere, and the reaction was carried out at room temperature for 0.5 hour. After the reaction was over, silica gel was added to the filtrate to produce sand after filtration. The crude product was obtained by silica gel column chromatography and was then washed with methanol or pentane-DCM to obtain 4cr as a green solid product in a yield of 59%.

As the paragraph descriping shows that 246047-72-3 is playing an increasingly important role.

Reference£º
Patent; Zannan Science And Technology (Shanghai) Co., Ltd.; Zhan Zhengyun; (102 pag.)CN104262403; (2017); B;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

246047-72-3, (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium is a ruthenium-catalysts compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: To a Schlenk flask charged with Grubbs? catalyst 2 (0.42 g,0.50 mmol) and CuCl (0.05 g, 0.50 mmol), compound 14 (or 15, 16)(0.6 mmol) in 10 mL dry dichloromethane was added at room temperature under N2. The resulting mixture was stirred for 40 min at 40 C. After being cooled to room temperature, the reaction mixturewas filtered and the clear filtrate was collected. The solvent from the filtrate was evaporated under vacuum to give a residue. The residue was purified by silica gel chromatography (CH2Cl2:ethyl acetate 2:1 or pentanes: ethyl acetate 3:2 or 1:1) to givethe desired product as a green crystalline solid.

246047-72-3 (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium 11147261, aruthenium-catalysts compound, is more and more widely used in various.

Reference£º
Article; Zhang, Yiran; Shao, Mingbo; Zhang, Huizhu; Li, Yuqing; Liu, Dongyu; Cheng, Yu; Liu, Guiyan; Wang, Jianhui; Journal of Organometallic Chemistry; vol. 756; (2014); p. 1 – 9;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

246047-72-3, (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium is a ruthenium-catalysts compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

To a solution of 6e (33.0 mg, 0.05 mmol) in anhydrous CH2Cl2 (6.0 ml) was added 2ndgeneration Grubbs catalyst (39.7 mg, 0.05 mmol) and CuCl (I) (4.6 mg, 0.05 mmol)under nitrogen at 30 C and stirred for 3 h. The reaction mixture was concentrated invacuo, and the residue was purified by column chromatography on silica gel (hexane /CH2Cl2 = 1 / 1) to give 2i (25.2 mg, 46%).Green crystals; mp 116.3-117.0 C; 1H NMR (270 MHz, CDCl3) delta 0.86 (d, J = 6.2 Hz,6H), 2.50 (br s, 18H), 4.23 (s, 4H), 4.45-4.54 (m, 1H), 7.07-7.12 (m, 6H), 7.26-7.54 (m,3H), 7.62 (d, J = 2.2 Hz, 1H), 7.80-7.87 (m, 4H), 16.51 (s, 1H); 19F (466 MHz, CDCl3)delta -80.6 (3F), 109.6 (2F), -121.1 (4F), -121.7 (4F), -122.5 (2F), -125.9 (2F); 13C NMR(68 MHz, CDCl3) delta 15.3, 22.1, 22.7, 66.0, 77.3, 110.3-119.9 (m, C8F17), 123.9, 124.3,124.7, 126.4, 127.3, 127.7, 127.9, 128.2, 129.1, 131.7, 132.8, 133.5, 133.7, 135.8, 136.3,155.8; IR (FT) 2919, 2360, 1605, 1481, 1398, 1242, 1207, 1145, 1109, 1094, 743 cm-1;HRMS (FAB) m/z [M+H]+ calcd for C49H44Cl2F17N2ORu 1172.1689; found 1172.1731.

The synthetic route of 246047-72-3 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Kobayashi, Yuki; Suzumura, Naoki; Tsuchiya, Yuki; Goto, Machiko; Sugiyama, Yuya; Shioiri, Takayuki; Matsugi, Masato; Synthesis; vol. 49; 8; (2017); p. 1796 – 1807;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.246047-72-3,(1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium,as a common compound, the synthetic route is as follows.

Grubbs second generation catalyst (100 mg, 0.117 mmol), 2-[(2,6-dimethylphenylimino)methyl]phenol (pKa: 8.85+/-0.30) (0.117 mmol), silver (I) carbonate (16.27 mg, 0.058 mmol), and THF (2 ml) were reacted at room temperature during 2 h. The solvent was evaporated and crude reaction product purified on a chromatography column to give an orange-brown complex. Yield 22%.

The synthetic route of 246047-72-3 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; Telene S.A.S.; US2011/65925; (2011); A1;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

246047-72-3, (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium is a ruthenium-catalysts compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

After a 50 mL two-necked flask was purged with argon, the ligand 3ch (10 mmol), 30 mL of CuCl (30 mmol, 3 eq) and 30 mL of dry DCM were sequentially added and the mixture was purged three times with argon to protect the closed system with argon balloon. Ruthenium complex 1b (12 mmol) was added under argon atmosphere, and the reaction was carried out at room temperature for 0.5 hour. After the reaction was over, silica gel was added to the filtrate to produce sand. The crude product was obtained by silica gel column chromatography, and then washed with methanol or pentane-DCM to obtain a green solid product 4ch, yield: 74%.

The synthetic route of 246047-72-3 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; Zannan Science And Technology (Shanghai) Co., Ltd.; Zhan Zhengyun; (102 pag.)CN104262403; (2017); B;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

246047-72-3, (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium is a ruthenium-catalysts compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

A 50 mL two-necked flask was purged with argon and the ligands 3cy (10mmol), CuCl (30mmol, 3eq) and 30mL of dry DCM were sequentially added and the mixture was purged three times with argon to protect the closed system with argon balloon. Ruthenium complex 1b (12 mmol) was added under argon atmosphere, and the reaction was carried out at room temperature for 0.5 hour. After the reaction was over, silica gel was added to the filtrate to produce sand after filtration. The crude product was obtained by silica gel column chromatography and then washed with methanol or pentane-DCM to obtain 4cy green solid product in a yield of 70%.

The synthetic route of 246047-72-3 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; Zannan Science And Technology (Shanghai) Co., Ltd.; Zhan Zhengyun; (102 pag.)CN104262403; (2017); B;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.246047-72-3,(1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium,as a common compound, the synthetic route is as follows.

A 50 mL two-necked flask was purged with argon and then the ligand 7e (10 mmol), CuCl (30 mmol, 3 eq) and 30 mL of dry DCM were sequentially added and the mixture was purged three times with argon to protect the closed system with an argon balloon. Ruthenium complex 1b (12 mmol) was added under argon atmosphere, and the reaction was carried out at room temperature for 0.5 hour. After the reaction was over, silica gel was added to the filtrate to produce sand. The crude product was obtained by silica gel column chromatography and then washed with methanol or pentane-DCM to obtain a green solid product 8e with a yield of 74%.

The synthetic route of 246047-72-3 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; Zannan Science And Technology (Shanghai) Co., Ltd.; Zhan Zhengyun; (102 pag.)CN104262403; (2017); B;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.246047-72-3,(1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium,as a common compound, the synthetic route is as follows.

To a dry 100 mL round-bottom flask containing a magnetic stirbar, under argon, was added 1.79 g (2.1 mmol, 1.0 equiv) [5], CuCl (521 mg, 5.28 mmol, 2.51 equiv), and 25 mL of anhydrous CH2Cl2. Ligand precursor [2] (403 mg, 2.1 mmol, 1.0 equiv) was added to the reddish solution in 20 mL of CH2Cl2 at room temperature. A reflux condenser was added and the mixture was heated for 70 minutes, under argon. The crude product was concentrated and loaded onto silica gel and eluted with 2:1 pentane:CH2Cl2 then 1:1 pentane:CH2Cl2 to remove a dark green band. The column was washed with CH2Cl2, then Et2O. The green and yellow bands were combined and concentrated under reduced pressure to yield a dark green solid. The solvents are removed under reduced pressure and the solid was crystallized from hexane to yield 1.07 g (1.70 mmol, 85%) of [6]. 1H NMR (300 MHz, CDCl3) delta: 16.56 (s, 1H, Ru=CHAr), 7.48 (m, 1H, aromatic CH), 7.07 (s, 4H, mesityl aromatic CH), 6.93 (dd, J=7.4 Hz, 1.6 Hz, 1H, aromatic CH), 6.85 (dd, J=7.4 Hz, 1H, aromatic CH), 6.79 (d, J=8.6 Hz, 1H, aromatic CH) 4.90 (septet, J=6.3 Hz, 1H, (CH3)2CHOAr), 4.18 (s, 4H, N(CH2)2N), 2.48 (s, 12H, mesityl o-CH3), 2.40 (s, 6H, mesityl p-CH3), 1.27 (d, J=5.9 Hz, 6H, (CH3)2CHOAr. 13C NMR (75 MHz, CDCl3) delta: 296.8 (q, J=61.5 Hz), 211.1, 152.0, 145.1, 145.09, 138.61, 129.4 (d, JNC 3.9 Hz), 129.3, 129.2, 122.6, 122.1, 122.8, 74.9 (d, JOC 10.7 Hz), 51.4, 30.9, 25.9, 21.01.

246047-72-3 (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium 11147261, aruthenium-catalysts compound, is more and more widely used in various.

Reference£º
Patent; MATERIA, INC.; Pederson, Richard L.; Woertink, Jason K.; Haar, Christopher M.; Gindelberger, David E.; Schrodi, Yann; (13 pag.)US9504997; (2016); B2;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

246047-72-3, (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium is a ruthenium-catalysts compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

Example 3 – Synthesis of the complex 3 according to the invention The commercially available complex G (200 mg, 0.24 mmol) was placed in a flask, to which methylene chloride was added (6 ml). This was followed by adding the compound of the formula: (63 mg, 0.47 mmol) and tricyclohexylphosphine (132 mg, 0.47 mmol). The resulting solution was stirred at a temperature of 40C for 5 hours. The reaction mixture was introduced at the top of a chromatographic column packed with silica gel (eluent: ethyl acetate/cyclohexane, 0 to 10 vol.%). After evaporating the solvents, the complex 3 was obtained as a green solid (140 mg, 72% yield). 3 H NMR (500 MHz, CD2Cl2) delta ppm: 15.85 (s, 1H), 7.07 (s, 1H), 7.00-6.96 (m, 3H), 6.66 (d, J = 8.4 Hz, 1H), 6.44 (dd, J = 7.7, 1.4 Hz, 1H), 6.24 (s, 1H), 6.20 (t, J = 7.2 Hz, 1H), 4.01-3.96 (m, 1H), 3.83-3.70 (m, 2H), 3.64-3.59 (m, 1H), 2.63 (s, 3H), 2.54 (s, 3H), 2.50 (s, 3H), 2.35 (s, 3H), 2.27 (s, 3H), 1.66-1.50 (m, 13H), 1.29 (s, 3H), 1.11-0.70 (m, 20H). 13C NMR: (125 MHz, CD2CI2) delta ppm: 281.36, 222.21, 221.66, 180.31, 148.30, 139.54, 139.17, 138.78, 137.63, 137.32, 136.98, 134.69, 130.23, 130.05, 129.70, 129.00, 122.38, 116.17, 111.26, 32.52, 32.39, 29.45, 28.92, 28.23, 28.15, 28.12, 28.04, 27.34, 27.03, 21.33, 21.14, 19.40, 18.92, 18.66, 16.76. 31P NMR (124.5 MHz, CDCI3) delta ppm: 29.11.

246047-72-3 (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium 11147261, aruthenium-catalysts compound, is more and more widely used in various.

Reference£º
Patent; APEIRON SYNTHESIS S.A.; SKOWERSKI, Krzysztof; BIENIEK, Micha?; WO2014/16422; (2014); A1;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

246047-72-3, (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium is a ruthenium-catalysts compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

Grubbs second generation catalyst (100 mg, 0.117 mmol), 2-[(2,4,6-trimethylphenylimino)methyl]phenol (pKa: 8.84+/- 0.30) (0.117 mmol), silver (I) carbonate (16.27 mg, 0.058 mmol), and THF (2 ml) were reacted at room temperature during 2 h. The solvent was evaporated and crude reaction product purified on chromatography column to give an orange-brown complex. Yield 30%.

246047-72-3 (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium 11147261, aruthenium-catalysts compound, is more and more widely used in various.

Reference£º
Patent; Telene SAS; EP2151445; (2010); A1;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI