Category: 23856-20-4

In general, if the atoms that make up the ring contain heteroatoms, such rings become heterocycles, and organic compounds containing heterocycles are called heterocyclic compounds. An article called Synthesis and evaluation of aniline headgroups for alkynyl thienopyrimidine dual EGFR/ErbB-2 kinase inhibitors, published in 2009-03-01, which mentions a compound: 23856-20-4, Name is 1-Benzyl-5-nitro-1H-indazole, Molecular C14H11N3O2, Application In Synthesis of 1-Benzyl-5-nitro-1H-indazole.

Aniline ‘headgroups’ were synthesized and incorporated into an alkynyl thienopyrimidine series of EGFR and ErbB-2 inhibitors. Potent inhibition of enzyme activity and cellular proliferation was observed In certain instances, protein binding was reduced and oral exposure was found to be somewhat improved relative to compounds containing the reference aniline.

Here is a brief introduction to this compound(23856-20-4)Application In Synthesis of 1-Benzyl-5-nitro-1H-indazole, if you want to know about other compounds related to this compound(23856-20-4), you can read my other articles.

Reference:
Highly efficient and robust molecular ruthenium catalysts for water oxidation,
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

Gambouz, Khadija; Abbouchi, Abdelmoula El; Nassiri, Sarah; Suzenet, Franck; Bousmina, Mostapha; Akssira, Mohamed; Guillaumet, Gerald; El Kazzouli, Said published the article 《Palladium-Catalyzed Oxidative Arylation of 1H-Indazoles with Arenes》. Keywords: indazole arene oxidative arylation palladium catalyst; arylated indazole preparation.They researched the compound: 1-Benzyl-5-nitro-1H-indazole( cas:23856-20-4 ).Category: ruthenium-catalysts. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. In addition, there is a lot of other information about this compound (cas:23856-20-4) here.

A simple method for the direct Pd(OAc)2-catalyzed oxidative arylation of inactivated 1H-indazole derivatives with simple arenes is reported. This method exhibits good reaction efficiency and good functional-group tolerance. Using the developed method, 28 arylated products, e.g., I, were prepared in yields up to 80%.

Here is a brief introduction to this compound(23856-20-4)Category: ruthenium-catalysts, if you want to know about other compounds related to this compound(23856-20-4), you can read my other articles.

Reference:
Highly efficient and robust molecular ruthenium catalysts for water oxidation,
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

Terol, A.; Robbe, Y.; Fernandez, J. P.; Chapat, J. P.; Granger, R.; Fatome, M.; Andrieu, L. published the article 《Study on radioprotectants. XV. Indazole derivatives》. Keywords: indazole derivative radioprotective; nitroindazole radioprotective.They researched the compound: 1-Benzyl-5-nitro-1H-indazole( cas:23856-20-4 ).Reference of 1-Benzyl-5-nitro-1H-indazole. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. In addition, there is a lot of other information about this compound (cas:23856-20-4) here.

Of the 23 indazole derivatives (I) studied, the I nitrates showed the greatest radioprotective activity. In mice receiving lethal doses of 60Co radiation, 6-nitroindazole (I: R1 = R2 = R4 = H; R3 = NO2) [7597-18-4] (1/2 of LD50, i.p.) was 90% effective.

Here is a brief introduction to this compound(23856-20-4)Reference of 1-Benzyl-5-nitro-1H-indazole, if you want to know about other compounds related to this compound(23856-20-4), you can read my other articles.

Reference:
Highly efficient and robust molecular ruthenium catalysts for water oxidation,
Catalysts | Special Issue : Ruthenium Catalysts – MDPI