In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called A modified approach for the site-selective direct C-6 arylation of benzylated uracil, published in 2019-12-26, which mentions a compound: 376581-24-7, mainly applied to methoxybenzyl methylpyrimidinedione aryl preparation regioselective; aryl halide methoxybenzyl methylpyrimidinedione arylation palladium catalyst; boronic acid aryl methoxybenzyl methylpyrimidinedione arylation palladium catalyst, Electric Literature of C9H8BNO2.
An efficient methodol. is reported for the regioselective C-6 arylation of protected uracil via the palladium catalyzed C-H functionalization of 1-(4-methoxybenzyl)-3-methylpyrimidine-2,4(1H,3H)-dione with (hetero)aryl halides and boronic acids ArX (Ar = 3,4-difluorophenyl, quinolin-3-yl, 2H-1,3-benzodioxol-5-yl, etc.; X = I, Br, B(OH)2, BF3K, OTf). Utilization of the Pd(OAc)2/xantphos catalytic system with a stoichiometric amount of CuI and DBU as the base was vital for the success of this protocol. The methodol. is facile and compatible with aryl bromides, iodides and boronic acids and hence affords broad substrate scope and diversity.
The article 《A modified approach for the site-selective direct C-6 arylation of benzylated uracil》 also mentions many details about this compound(376581-24-7)Electric Literature of C9H8BNO2, you can pay attention to it, because details determine success or failure.
Reference:
Highly efficient and robust molecular ruthenium catalysts for water oxidation,
Catalysts | Special Issue : Ruthenium Catalysts – MDPI