In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Synthesis and biological evaluation of benzothiazole derivatives as potent antitumor agents, published in 2005-07-15, which mentions a compound: 2407-11-6, mainly applied to benzothiazolediamine preparation antitumor, Application of 2407-11-6.
Based on 2-methyl-4-nitro-2H-pyrazole-3-carboxylic acid [2-(cyclohexanecarbonylamino)benzothiazol-6-yl]amide, which shows selective cytotoxicity against tumorigenic cell lines, 2,6-dichloro-N-[2-(cyclopropanecarbonylamino)benzothiazol-6-yl]benzamide (I) was designed and synthesized as a biol. stable derivative containing no nitro group. The highly potent derivative I exhibited excellent in vivo inhibitory effect on tumor growth.
Although many compounds look similar to this compound(2407-11-6)Application of 2407-11-6, numerous studies have shown that this compound(SMILES:O=[N+](C1=CC=C2N=C(Cl)SC2=C1)[O-]), has unique advantages. If you want to know more about similar compounds, you can read my other articles.
Reference:
Highly efficient and robust molecular ruthenium catalysts for water oxidation,
Catalysts | Special Issue : Ruthenium Catalysts – MDPI