The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: Quinolin-6-ylboronic acid( cas:376581-24-7 ) is researched.COA of Formula: C9H8BNO2.Tan, Jiajing; Chen, Yonggang; Li, Hongmei; Yasuda, Nobuyoshi published the article 《Suzuki-Miyaura Cross-Coupling Reactions of Unprotected Haloimidazoles》 about this compound( cas:376581-24-7 ) in Journal of Organic Chemistry. Keywords: haloimidazole aryl boronic acid Suzuki Miyaura cross coupling; Suzuki Miyaura cross coupling palladium catalyst; substituted imidazole preparation. Let’s learn more about this compound (cas:376581-24-7).
An efficient protocol for the palladium-catalyzed Suzuki-Miyaura cross-coupling reaction of unprotected haloimidazoles is reported. The relatively mild reaction conditions allow for ready access to a wide array of functionalized imidazole derivatives in good to excellent yields. The synthetic utility of this method is demonstrated by the total synthesis of nortopsentin D.
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