So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Forlani, Luciano; Todesco, Paolo E. researched the compound: 2-Chloro-6-nitrobenzo[d]thiazole( cas:2407-11-6 ).Safety of 2-Chloro-6-nitrobenzo[d]thiazole.They published the article 《Base catalysis in reactions between 2-halo-6-nitrobenzothiazoles and aliphatic amines in benzene. Part II》 about this compound( cas:2407-11-6 ) in Gazzetta Chimica Italiana. Keywords: benzothiazole halonitro amine substitution; substitution halonitrobenzothiazole amine catalysis. We’ll tell you more about this compound (cas:2407-11-6).
Rate data for reactions of I (X = Br, Cl) with amines (e.g. piperidine, BuNH2, Me3CNH2) show the presence of a base-catalyzed pathway which involves bifunctional catalysis, basic on the entering group, acidic on the leaving group.
The article 《Base catalysis in reactions between 2-halo-6-nitrobenzothiazoles and aliphatic amines in benzene. Part II》 also mentions many details about this compound(2407-11-6)Safety of 2-Chloro-6-nitrobenzo[d]thiazole, you can pay attention to it, because details determine success or failure
Reference:
Highly efficient and robust molecular ruthenium catalysts for water oxidation,
Catalysts | Special Issue : Ruthenium Catalysts – MDPI