Application of 271-95-4. The fused heterocycle is formed by combining a benzene ring with a single heterocycle, or two or more single heterocycles. Compound: 1,2-Benzisoxazole, is researched, Molecular C7H5NO, CAS is 271-95-4, about Method development and validation of RP-HPLC method for determination of new antipsychotic agent in paliperidone palmitate bulk drug. Author is Swarnalatha, G.; Vijayakumar, B.; Jothieswari, D.; Reddy, P. Jaya Chandra; Mohankumar, M..
A simple, precise, rapid, reproducible, accurate and stability indicating RP-HPLC method has been developed for the determination of new antipsychotic agent paliperidone in pharmaceutical formulation. zorbax -SB-Ph, 150 × 4.6mm; 3.5μm particle size column was used with variable wavelength UV detector. The mobile phase consisting of PH 4 Buffer and Acetonitrile 80:20 volume/volume was used. The flow rate was 1 mL/min and the effluent was monitored at 238 nm. The retention time of drug was 0.9. The method was linear over the concentration range of 1.0 mg/mL. The method precision for the determination of assay was below 2%RSD. The percentage recovery of paliperidone was 85-115%. The validation of method was carried out utilizing ICH Q2 (R1) guidelines.
After consulting a lot of data, we found that this compound(271-95-4)Application of 271-95-4 can be used in many types of reactions. And in most cases, this compound has more advantages.
Reference:
Highly efficient and robust molecular ruthenium catalysts for water oxidation,
Catalysts | Special Issue : Ruthenium Catalysts – MDPI