So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Liu, Bao; You, Qi Dong; Li, Zhi Yu researched the compound: 2-Chloro-6-nitrobenzo[d]thiazole( cas:2407-11-6 ).COA of Formula: C7H3ClN2O2S.They published the article 《Design, synthesis and antitumor activity of 6,7-disubstituted-4-(heteroarylamino)quinoline-3-carbonitrile derivatives》 about this compound( cas:2407-11-6 ) in Chinese Chemical Letters. Keywords: quinolinecarbonitrile preparation antitumor neoplasm. We’ll tell you more about this compound (cas:2407-11-6).
Twelve new 6,7-disubstituted-4-(benzothiazol-6-ylamino)quinoline-3-carbonitriles I (R1 = H2N, Me2N, Et2N; R2 = Et2N, N-piperidinyl, N-morpholinyl, etc.) were synthesized. The cytotoxicity of the new compounds was evaluated in AGS, HepG2 and HT-29 cell lines. Several synthesized compounds displayed more potent cytotoxic activities than Bosutinib. Compound I (R1 = R2 = Et2N) exhibited the most potent antitumor activity among the tested compounds
After consulting a lot of data, we found that this compound(2407-11-6)COA of Formula: C7H3ClN2O2S can be used in many types of reactions. And in most cases, this compound has more advantages.
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Highly efficient and robust molecular ruthenium catalysts for water oxidation,
Catalysts | Special Issue : Ruthenium Catalysts – MDPI