Analyzing the synthesis route of 271-95-4

Although many compounds look similar to this compound(271-95-4)Recommanded Product: 1,2-Benzisoxazole, numerous studies have shown that this compound(SMILES:C12=CC=CC=C1ON=C2), has unique advantages. If you want to know more about similar compounds, you can read my other articles.

Most of the compounds have physiologically active properties, and their biological properties are often attributed to the heteroatoms contained in their molecules, and most of these heteroatoms also appear in cyclic structures. A Journal, Zeszyty Naukowe Politechniki Slaskiej, Chemia called Syntheses of heterocyclic systems from some hydroxylamine and hydrazine derivatives, Author is Suwinski, Jerzy, which mentions a compound: 271-95-4, SMILESS is C12=CC=CC=C1ON=C2, Molecular C7H5NO, Recommanded Product: 1,2-Benzisoxazole.

Formation of heterocyclic compounds from NH2OH and N2H4 derivatives is reviewed. Treating NH2OH with α-benzylidene-ketones gave α,β-unsaturated oximes, NH2OH addition to the double bond, and isoxazolines. Reaction of NH2OH with α-benzylketones gives oximes which gave quinolines when heated in organic acid oximes. Treating NH2OH with carboxylic acid derivatives gave hydroxamic acids, from which those containing a β-Ph cyclize to benzolactams in polyphosphoric acid medium. Condensing hydroxylamine-O-sulfonic acid (I) with pyridylalkanones gives stable oxime hydrosulfates. Such derivatives of α-pyridylcclohexanone cyclized to pyrazolopyridine system under very mild conditions. Treating I with o-HOC6H4CHO in alk. medium gave benzisoxazole. Reaction of O-sulfonylhydroxylamines with N-heterocycles gave N-aminoheterocycles, which were also obtained from reactions of hydrazines. Treating the N-aminoheterocycles with suitable dicarbonyl compounds, pyrylium salt, pyrone, or diethoxytetrahydrofuran gave N,N-linked bi(heteroaryls).

Although many compounds look similar to this compound(271-95-4)Recommanded Product: 1,2-Benzisoxazole, numerous studies have shown that this compound(SMILES:C12=CC=CC=C1ON=C2), has unique advantages. If you want to know more about similar compounds, you can read my other articles.

Reference:
Highly efficient and robust molecular ruthenium catalysts for water oxidation,
Catalysts | Special Issue : Ruthenium Catalysts – MDPI