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Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 376581-24-7, is researched, SMILESS is OB(C1=CC=C2N=CC=CC2=C1)O, Molecular C9H8BNO2Journal, Article, Research Support, Non-U.S. Gov’t, Journal of Organic Chemistry called Copper-Catalyzed Anomeric O-Arylation of Carbohydrate Derivatives at Room Temperature, Author is Verdelet, Tristan; Benmahdjoub, Sara; Benmerad, Belkacem; Alami, Mouad; Messaoudi, Samir, the main research direction is aryl glycoside preparation anomeric arylation sugar lactol arylboronic acid.Application In Synthesis of Quinolin-6-ylboronic acid.

Direct and practical anomeric O-arylation of sugar lactols with substituted arylboronic acids has been established. Using copper catalysis at room temperature under an air atm., the protocol proved to be general, and a variety of aryl O-glycosides have been prepared in good to excellent yields. Furthermore, this approach was extended successfully to unprotected carbohydrates, including α-mannose, and it was demonstrated here how the interaction between carbohydrates and boronic acids can be combined with copper catalysis to achieve selective anomeric O-arylation.

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Reference:
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