Safety of 1-Boc-4-Bromoindole. So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic. Compound: 1-Boc-4-Bromoindole, is researched, Molecular C13H14BrNO2, CAS is 676448-17-2, about Using Chlorotrifluoroethane for Trifluoroethylation of (Hetero)aryl Bromides and Chlorides via Nickel Catalysis.
A nickel-catalyzed reductive cross-coupling between industrial chem. CF3CH2Cl and (hetero)aryl bromides and chlorides was reported. The reaction was synthetically simple without the preparation of arylmetals and exhibits high functional group tolerance. The utility of this protocol was demonstrated by the late-stage modification of pharmaceuticals, providing a facile route for medicinal chem.
This literature about this compound(676448-17-2)Safety of 1-Boc-4-Bromoindolehas given us a lot of inspiration, and I hope that the research on this compound(1-Boc-4-Bromoindole) can be further advanced. Maybe we can get more compounds in a similar way.
Reference:
Highly efficient and robust molecular ruthenium catalysts for water oxidation,
Catalysts | Special Issue : Ruthenium Catalysts – MDPI