Zeng, Xiaojun; Yan, Wenhao; Zacate, Samson B.; Cai, Aijie; Wang, Yufei; Yang, Dongqi; Yang, Kundi; Liu, Wei published the article 《Copper-Catalyzed Deaminative Difluoromethylation》. Keywords: copper catalyst deaminative difluoromethylation alkyl amine; copper; deamination; difluoromethylation; homogeneous catalysis; pyridinium salts.They researched the compound: Copper(I) tetra(acetonitrile) tetrafluoroborate( cas:15418-29-8 ).Product Details of 15418-29-8. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. In addition, there is a lot of other information about this compound (cas:15418-29-8) here.
The difluoromethyl group (CF2H) is considered to be a lipophilic and metabolically stable bioisostere of an amino (NH2) group. Therefore, methods that can rapidly convert an NH2 group into a CF2H group would be of great value to medicinal chem. The authors report herein an efficient Cu-catalyzed approach for the conversion of alkyl pyridinium salts, which can be readily synthesized from the corresponding alkyl amines, to their alkyl difluoromethane analogs. This method tolerates a broad range of functional groups and can be applied to the late-stage modification of complex amino-containing pharmaceuticals.
There is still a lot of research devoted to this compound(SMILES：[Cu+](N#CC)(N#CC)(N#CC)N#CC.[B+3]([F-])([F-])([F-])[F-])Product Details of 15418-29-8, and with the development of science, more effects of this compound(15418-29-8) can be discovered.
Reference:
Highly efficient and robust molecular ruthenium catalysts for water oxidation,
Catalysts | Special Issue : Ruthenium Catalysts – MDPI