In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Formation of Macrocycles by Catalytic Intramolecular Aromatic Cycloaddition of Metal Carbenes to Remote Arenes, published in 1996-08-21, which mentions a compound: 138984-26-6, mainly applied to macrocyclic compound preparation; intramol aromatic cycloaddition metal carbene arene; macrocyclization diazoacetate phenylalkoxyalkyl rhodium, Safety of Dirhodium(II) tetrakis(caprolactam).
Diazoacetates derived from diols underwent dirhodium(II) carboxylate-catalyzed intramol. cycloaddition to form macrocyclic lactones or ketones in moderate to high isolated yields. For example, the cycloaddition of diazoacetic acid [2-[(phenylmethoxy)methyl]phenyl]methyl ester (I) gave the macrocyclic compound II and homologs thereof, such as III. Addition to the remote benzyl group occurred mainly at the 1,2-position to form disubstituted cycloheptatrienes in a bicyclo[8.5.0]-framework, but with p-methoxybenzyl derivatives addition was mainly at the 3,4-position to form a bicyclo[8.3.2]-framework. Dirhodium(II) perfluorobutyrate was the preferred catalyst for these transformations that were remarkably free of competing intramol. reactions; however, intramol. cyclopropanation of the allylic double bond was the exclusive outcome in dirhodium(II) caprolactamate-catalyzed reactions of cis-4-benzyloxy-2-buten-1-yl diazoacetate.
There is still a lot of research devoted to this compound(SMILES：C12=O[Rh+2]3(O=C4[N-]5CCCCC4)([N-]6C(CCCCC6)=O7)[N-](CCCCC8)C8=O[Rh+2]357[N-]1CCCCC2)Safety of Dirhodium(II) tetrakis(caprolactam), and with the development of science, more effects of this compound(138984-26-6) can be discovered.
Reference:
Highly efficient and robust molecular ruthenium catalysts for water oxidation,
Catalysts | Special Issue : Ruthenium Catalysts – MDPI