Dowd, Paul; Kaufman, Christopher; Kaufman, Paul published the article 《β-Methylene-DL-asparagine》. Keywords: methyleneaspartic acid; aspartic acid methylene.They researched the compound: 2-Bromopropanenitrile( cas:19481-82-4 ).Related Products of 19481-82-4. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. In addition, there is a lot of other information about this compound (cas:19481-82-4) here.
The title compound (I) was prepared from MeCHBrCN (II) and CH2(CO2CMe3)2 (III) in several steps. Thus, II was condensed with III in THF containing NaH to give malonate IV (R = H), which was treated with NaH in THF and then brominated with Br2 to give IV (R = Br), which was dehydrobrominated by treatment with Na2CO3/pyridine to give a 10:90 mixture of butenoates V (R = H) (VI) and VII. VII was converted to VI by treatment with NaH followed by quenching with HCl. A mixture of VI and VII were treated with NaH and then with chloramine to give V (R = NH2), which was hydrolyzed by 20% HCl to give I.HCl, which was treated with aqueous NaOH to give I.
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Highly efficient and robust molecular ruthenium catalysts for water oxidation,
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