Synthetic Route of 301224-40-8. Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 301224-40-8, Name is (1,3-Dimesitylimidazolidin-2-ylidene)(2-isopropoxybenzylidene)ruthenium(VI) chloride
The synthesis of new ruthenium-based catalysts applicable for both homogeneous and heterogeneous metathesis is described. Starting from the Hoveyda-Grubbs first generation (1) and the Hoveyda-Grubbs second generation (2) catalysts the homogeneous catalysts [RuCl((RO)3Si-C3H6-N(R?)-CO-C3F6-COO)({double bond, long}CH-o-O-iPr-C6H4)(SIMes)] (4: R = Et, R? = H; 5: R = R? = Me) (SIMes = 1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidene) were prepared by substitution of one chloride ligand with trialkoxysilyl functionalized silver carboxylates (RO)3Si-C3H6-N(R?)-CO-C3F6-COOAg (3a: R = Et, R? = H; 3b: R = R? = Me). These homogeneous ruthenium-species are among a few known examples with mixed anionic ligands. Exchange of both chloride ligands afforded the catalysts [Ru((RO)3Si-C3H6-N(R?)-CO-C3F6-COO)({double bond, long}CH-o-O-iPr-C6H4)(SIMes)] (9: R = Et, R? = H; 11: R = R? = Me) and [Ru((RO)3Si-C3H6-N(R?)-CO-C3F6-COO)({double bond, long}CH-o-O-iPr-C6H4)(PCy3)] (8: R = Et, R? = H; 10: R = R? = Me). The reactivity of the new complexes was tested in homogeneous ring-closing metathesis (RCM) of N,N-diallyl-p-toluenesulfonamide and TONs of up to 5000 were achieved. Heterogeneous catalysts were obtained by reaction of 4, 5 and 8-11 with silica gel (SG-60). The resultant supported catalysts 4a, 5a, 8a-11a showed reduced activity compared to their homogenous analogues, but rival the activity of similar heterogeneous systems.
If you are hungry for even more, make sure to check my other article about 301224-40-8. Reference of 301224-40-8
Reference：
Highly efficient and robust molecular ruthenium catalysts for water oxidation,
Catalysts | Special Issue : Ruthenium Catalysts – MDPI