Children learn through play, and they learn more than adults might expect. Science experiments are a great way to spark their curiosity, get their minds active, and encourage them to do something that doesn’t involve a screen. 246047-72-3, C46H65Cl2N2PRu. A document type is Article, introducing its new discovery., Recommanded Product: (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium
Three new classes of conformationally constrained peptidomimetics, derived from modified alpha- and beta-amino acids, have been prepared by ring closing metathesis (RCM). The first involves Calpha-N? cyclisation of the peptidic diene (23, 24, 26), the second Cbeta2-N? cyclisation (27, 28, 29), and the third N-Cbeta2 cyclisation (30). The key C-centred olefin of the dienes was introduced by stereoselective alpha-allylation of either an alpha- or beta-amino acid. The normal favourable influence of a tertiary amide linker in the diene towards RCM is negated by significant steric congestion, and the combination of a secondary amide linker and alpha,alpha-disubstitution promotes ring contraction on RCM.
Interested yet? Keep reading other articles of 246047-72-3!, Recommanded Product: (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium
Reference：
Highly efficient and robust molecular ruthenium catalysts for water oxidation,
Catalysts | Special Issue : Ruthenium Catalysts – MDPI