Synthetic Route of 246047-72-3, Chemistry can be defined as the study of matter and the changes it undergoes. You’ll sometimes hear it called the central science because it is the connection between physics and all the other sciences, starting with biology.246047-72-3, Name is (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium, molecular formula is C46H65Cl2N2PRu. In a patent, introducing its new discovery.
The synthesis of the phytotoxic lactone herbarumin III in 11 % overall yield by fermentation of broth and mycelium of the fungus Phoma herbarum is described. Keck’s asymmetric allylation and Sharpless epoxidation are applied to build the key fragment of the compound. A ring closing metathesis and esterification with 5-hexanoic acid are used to obtain the compound. The synthesis is initiated by the application of the catalytic asymmetric allyl protocol. Chain elongation of the aldehyde through Wittig olefination with triphenyl carbethoxymethyl phosphonium chloride supported on alumina under microwave irradiation provided the alpha, beta – unsaturated ester as the major product. The ring opening metathesis with Grubbs second-generation catalyst gave Herbarumin III as a clear oil. The complete procedure involved the synthesis of the compound from n-butanal in 11 % overall yield.
If you are interested in 246047-72-3, you can contact me at any time and look forward to more communication.Synthetic Route of 246047-72-3
Reference：
Highly efficient and robust molecular ruthenium catalysts for water oxidation,
Catalysts | Special Issue : Ruthenium Catalysts – MDPI