Reference of 15746-57-3, Children learn through play, and they learn more than adults might expect. Science experiments are a great way to spark their curiosity, get their minds active, and encourage them to do something that doesn’t involve a screen. 15746-57-3, C20H16Cl2N4Ru. A document type is Article, introducing its new discovery.
Three new bis(2,2?-bipyridine)-heteroleptic Ru(II) dyads incorporating thienyl groups (n = 1?3, compounds 1, 2 and 3, respectively) appended to 1,10-phenanthroline were synthesized and characterized to investigate the impact of n on the photophysical and photobiological properties within the series. All three complexes showed unstructured emission near 618 nm from a triplet metal-to-ligand charge transfer (3MLCT) state with a lifetime (tauem) of approximately 1 mus. Transient absorption measurements revealed an additional excited state that was nonemissive and long-lived (tauTA = 43 mus for 2 and 27 mus for 3), assigned as a triplet intraligand (3IL) state that was accessible only in 2 and 3. All three complexes were strong singlet oxygen (1O2) sensitizers, with quantum yields (Phi?) for 2 and 3 being the largest (74?78%), and all three were photocytotoxic to cancer cells with visible light activation in the order: 3 > 2 > 1. Cell-free DNA photodamage followed the same trend, where potency increased with decreasing 3IL energy. Compounds 2 and 3 also showed in vitro photobiological effects with red light (625 nm), where their molar absorptivities were <100 m?1 cm?1. These findings highlight that Ru(II) dyads derived from alpha-oligothiophenes directly appended to 1,10-phenanthroline?namely 2 and 3?possess low-lying 3IL states that are highly photosensitizing, and they may therefore be of interest for photobiological applications such as photodynamic therapy (PDT). If you are hungry for even more, make sure to check my other article about 15746-57-3. Reference of 15746-57-3
Reference：
Highly efficient and robust molecular ruthenium catalysts for water oxidation,
Catalysts | Special Issue : Ruthenium Catalysts – MDPI