37366-09-9, Name is Dichloro(benzene)ruthenium(II) dimer, molecular formula is C12H12Cl4Ru2, belongs to ruthenium-catalysts compound, is a common compound. In a patnet, once mentioned the new application about 37366-09-9, Safety of Dichloro(benzene)ruthenium(II) dimer
Pd and Ru complexes bearing axially chiral ligands for the asymmetric hydrogenation of C=C and C=O double bonds
Complexes composed of either Pd or Ru as central metal and ligands with axial chirality in all cases were used as hydrogenation catalysts. The ligands were (R)- and (S)-6,6?-dimethyl-2,2?-diaminobiphenyl, (R)-(+)-1-1?-Bi(2-naphtylamine), (R)-2,2?-Bis(diphenylphosphino)-1, 1?-binaphthalene and (R)-2,2?-Bis(di-p-tolylphosphino)-1,1?- binaphthyl. The Pd(II) complexes had one diamine ligand and the Ru(II) complexes had one bisphosphine and one diamine ligand, forming seven member chelate rings with the metal center. The pro-chiral substrates used were itaconic acid, alpha-acetamidocinnamic acid and acetophenone. The Pd complexes showed 100% chemoselectivity toward the CC bond, and toward the CO bond in the case of Ru. The yield and enantiomeric excess versus time behavior was studied using a large substrate/catalyst ratio. The addition of an organic base to the reaction with Pd complexes enhanced yield and enantiomeric excess. Use of the (S)-diamine ligand in the complex favored the (R)-products. The best results with itaconic acid were 61% yield and 56% enantiomeric excess and 55% yield and 52% enantiomeric excess with alpha-acetamidocinnamic acid, both catalyzed by Pd(OCOCF3)2 ((S)-6,6?-dimethyl-2,2?- diaminobiphenyl) in 2,2,2-trifluoroethanol. In the case of the Ru catalysts, (S)-1-phenylethanol formed preferentially during hydrogenation of acetophenone. Potassium tert-butoxide stabilized the enantiomeric excess. The best result was 87% yield and 41% enantiomeric excess catalyzed by ((R)-2,2?-Bis(di-p- tolylphosphino)-1,1?-binaphthyl)-RuCl2-((R)-(+)-1-1?- Bi(2-naphtylamine)).
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Safety of Dichloro(benzene)ruthenium(II) dimer. In my other articles, you can also check out more blogs about 37366-09-9
Reference£º
Highly efficient and robust molecular ruthenium catalysts for water oxidation,
Catalysts | Special Issue : Ruthenium Catalysts – MDPI