Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics.In a document type is Article, the author is Curto, John M. and a compound is mentioned, 301224-40-8, (1,3-Dimesitylimidazolidin-2-ylidene)(2-isopropoxybenzylidene)ruthenium(VI) chloride, introducing its new discovery. 301224-40-8
Asymmetric synthesis of alpha-allyl-alpha-aryl alpha-amino acids by tandem alkylation/pi-allylation of alpha-iminoesters
The first asymmetric synthesis of alpha-allyl-alpha-aryl alpha-amino acids by means of a three-component coupling of alpha-iminoesters, Grignard reagents, and cinnamyl acetate is reported. Notably, the enolate from the tandem process provides a much higher level of reactivity and selectivity than the same enolate generated via direct deprotonation, presumably due to differences in the solvation/aggregation state. A novel method for removal of a homoallylic amine protecting group delivers the free amine congeners. The alpha-allyl group offers a means to generate further valuable alpha-amino acid structures as exemplified by ring closing metathesis to generate a higher ring homologue of alpha-aryl-proline.
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Highly efficient and robust molecular ruthenium catalysts for water oxidation,
Catalysts | Special Issue : Ruthenium Catalysts – MDPI