Day: November 13, 2020

As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 301224-40-8, name is (1,3-Dimesitylimidazolidin-2-ylidene)(2-isopropoxybenzylidene)ruthenium(VI) chloride This compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below., 301224-40-8

A further example of a synthesis producing an NHC containing cis complex is shown below. [0088] HII (200 mg) and P(OiPr)3 (5 eq) were stirred in for 72 h. The crude 65 was recrystallised from DCM/pentane. [0089] 1H (400 MHz, 298K): 16.05 (d, 1H, J=35.3 Hz, C?CH), 10.24 (d, 1H, J=9.7 Hz, Ph-H), 6.87-6.83 (m, 2H, Ph-H), 6.78 (s, 1H, Ph-H), 6.61 (s, 1H, Ph-H), 6.19-6.16 (m, 2H, Ph-H), 4.67 (brs, 2H, PO-CH-CH3), 4.09-4.06 (m, 1H, Ph-O-CH-CH3), 4.04 (brs, 1H, PO-CH-CH3), 3.43-3.40 (m, 1H), 3.16-3.02 (m, 3H), 2.89 (s, 3H, Mes-CH3), 2.58 (s, 3H, CH3), 2.46 (s, 3H, CH3), 2.42 (s, 3H, CH3), 2.18 (s, 3H, CH3), 1.92 (s, 3H, CH3), 1.48-0.80 (m, 24H, PO-CH-CH3). [0090] 31P{1H} (121.49 MHz, 298K): 128.7 (s)

301224-40-8, As the paragraph descriping shows that 301224-40-8 is playing an increasingly important role.

Reference£º
Patent; University Court of the University of St. Andrews; Cazin, Catherine; US2014/228563; (2014); A1;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product.15529-49-4, name is Dichlorotris(triphenylphosphino)ruthenium (II) An updated downstream synthesis route of 15529-49-4 as follows., 15529-49-4

General procedure: Diphosphine ligand (2.0 mmol) was dissolved in 10 mL of dichloromethane and the solution was added dropwise to a stirred solution of RuCl2(PPh3)3 (1.0 mmol) in 10 mL of dichloromethane. The reaction mixture was stirred approximately for 50 min at room temperature. The brown solution was filtered to remove the insoluble impurities. The solvent was reduced by a vacuum and the product was then precipitated by adding n-hexane. The yellow solid was filtered and washed three times with 20 mL of diethyl ether., 15529-49-4

15529-49-4 Dichlorotris(triphenylphosphino)ruthenium (II) 11007548, aruthenium-catalysts compound, is more and more widely used in various fields.

Reference£º
Article; Al-Noaimi, Mousa; Warad, Ismail; Abdel-Rahman, Obadah S.; Awwadi, Firas F.; Haddad, Salim F.; Hadda, Taibi B.; Polyhedron; vol. 62; (2013); p. 110 – 119;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

301224-40-8, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 301224-40-8, name is (1,3-Dimesitylimidazolidin-2-ylidene)(2-isopropoxybenzylidene)ruthenium(VI) chloride This compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.

Take Grubbs-HoveydaII catalyst (464.0mg, 0.74mmol),Compound II (201.0 mg, 0.9 mmol,) prepared in Example 1 was placed in a 25 mL round bottom flask.Add 15 mL of dry THF and stir at 800 r / min at room temperature for 30 min.After the reaction was completed, the solvent was dried with a vacuum pump to obtain a brown-red solid.Add n-hexane to the solid and stir thoroughly. At this time, the color of n-hexane will turn red. Centrifuge the mixture, discard the liquid, and dry the solid.Compound III (385 mg, yield: 70.6%) was obtained as a brown solid powder.

301224-40-8, As the paragraph descriping shows that 301224-40-8 is playing an increasingly important role.

Reference£º
Patent; Jilin Chemical College; Yu Xiaobo; Geng Shudong; Liu Guanchen; (14 pag.)CN110563769; (2019); A;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

301224-40-8, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 301224-40-8, name is (1,3-Dimesitylimidazolidin-2-ylidene)(2-isopropoxybenzylidene)ruthenium(VI) chloride This compound has unique chemical properties. The synthetic route is as follows.

HII 65 HII (200mg) and P(0’Pr)3 (5eq) were stirred in for 72h. The crude 65 was recrystallised from DCM/pentane. (400MHz, 298K): 16.05 (d, 1 H, J = 35.3 Hz, C=CH), 10.24 (d, 1 H, J = 9.7 Hz, Ph-H), 6.87-6.83 (m, 2H, Ph-H), 6.78 (s, 1 H, Ph-H), 6.61 (s, 1 H, Ph-H), 6.19-6.16 (m, 2H, Ph- H), 4.67 (brs, 2H, PO-CH-CH3), 4.09-4.06 (m, 1 H, Ph-0-CH-CH3), 4.04 (brs, 1 H, PO- CH-CH3), 3.43-3.40 (m, 1 H), 3.16-3.02 (m, 3H), 2.89 (s, 3H, Mes-CH3), 2.58 (s, 3H, CH3), 2.46 (s, 3H, CH3), 2.42 (s, 3H, CH3), 2.18 (s, 3H, CH3), 1.92 (s, 3H, CH3), 1.48- 0.80 (m, 24H, PO-CH-CH3).31P{1H} (121.49MHz, 298K): 128.7 (s)

With the complex challenges of chemical substances, we look forward to future research findings about 301224-40-8,belong ruthenium-catalysts compound

Reference£º
Patent; UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS; CAZIN, Catherine; WO2011/117571; (2011); A1;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

246047-72-3, Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials.246047-72-3, name is (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium A new synthetic method of this compound is introduced below.

General procedure: To a Schlenk flask charged with Grubbs? catalyst 2 (0.42 g,0.50 mmol) and CuCl (0.05 g, 0.50 mmol), compound 14 (or 15, 16)(0.6 mmol) in 10 mL dry dichloromethane was added at room temperature under N2. The resulting mixture was stirred for 40 min at 40 C. After being cooled to room temperature, the reaction mixturewas filtered and the clear filtrate was collected. The solvent from the filtrate was evaporated under vacuum to give a residue. The residue was purified by silica gel chromatography (CH2Cl2:ethyl acetate 2:1 or pentanes: ethyl acetate 3:2 or 1:1) to givethe desired product as a green crystalline solid.

246047-72-3, As the paragraph descriping shows that 246047-72-3 is playing an increasingly important role.

Reference£º
Article; Zhang, Yiran; Shao, Mingbo; Zhang, Huizhu; Li, Yuqing; Liu, Dongyu; Cheng, Yu; Liu, Guiyan; Wang, Jianhui; Journal of Organometallic Chemistry; vol. 756; (2014); p. 1 – 9;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

203714-71-0, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 203714-71-0, name is Dichloro(2-isopropoxyphenylmethylene)(tricyclohexylphosphine)ruthenium (II) This compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.

NHC ligand precursor 21 (9 mg, .03 mmol), KOz-Bu(F6) (6 mg, .03 mmol), and ruthenium complex 911 (13 mg, .02 mmol) were all combined in CgDbeta in a screw cap NMR tube in a glove box. The NMR tube was removed and heated at 600C for 2.5 hour in a fume hood. Conversion to catalyst 22 was determined to be 14% by proton NMR. 1H NMR (300 MHz, CDCl3) delta 17.19 (IH, s).

203714-71-0, 203714-71-0 Dichloro(2-isopropoxyphenylmethylene)(tricyclohexylphosphine)ruthenium (II) 10941020, aruthenium-catalysts compound, is more and more widely used in various fields.

Reference£º
Patent; MATERIA, INC.; CALIFORNIA INSTITUTE OF TECHNOLOGY; WO2007/75427; (2007); A1;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

15529-49-4, Dichlorotris(triphenylphosphino)ruthenium (II) is a ruthenium-catalysts compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

In a glove box, [RuCl2(PPh3)3] (0.25 mmol) was added to a schlenk flask equipped with a magnetic stir bar. The flask was then attached to a schlenk line and 3.4 mL of freshly distilled toluene added. The mixture was then rapidly stirred. A 1.7 mL toluene solution of Ph2PCH2CH2NH2, (0.50 mmol) in an NMR tube was then added via a cannula. Any residue in the NMR tube and cannula was washed into the flask with 1.7 mL of toluene. The light yellow mixture was then heated at 100 C. for 6 h. The yellow suspension that resulted was allowed to cool to RT before collecting the precipitate by filtration under Argon. The precipitate was then washed with 10.0 mL portions of toluene, three times (until colorless). The yellow solid was then dried in vacuo. Yield: 90%. Note: Excessive scraping of the product should be minimised to prevent the build-up of static electricity, 15529-49-4

The synthetic route of 15529-49-4 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; THE GOVERNORS OF THE UNIVERSITY OF ALBERTA; Bergens, Steven; John, Jeremy M.; US2014/163225; (2014); A1;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

246047-72-3, Adding a certain compound to certain chemical reactions, such as: 246047-72-3, name is (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 246047-72-3

To a solution of 1-isopropoxy-4-(perfluorodecyl)-2-vinylbenzene (35.5mg, 0.052mmol) in dry CH2Cl2 (4 mL) was added Grubbs 2nd generation (48.75 mg, 0.057 mmol) and CuCl (I) (8.2 mg, 0.083 mmol) under N2 at 35C and stirred for 3 h. The reaction mixture was concentrated in vacuo, and the residue was purified by column chromatography on silica gel (hexane / CH2Cl2 = 1 / 1) to give 1a (39.5mg, 65%).

246047-72-3, As the paragraph descriping shows that 246047-72-3 is playing an increasingly important role.

Reference£º
Article; Kobayashi, Yuki; Inukai, Sae; Kondo, Natsuki; Watanabe, Tomoko; Sugiyama, Yuya; Hamamoto, Hiromi; Shioiri, Takayuki; Matsugi, Masato; Tetrahedron Letters; vol. 56; 11; (2015); p. 1363 – 1366;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

15529-49-4, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 15529-49-4, name is Dichlorotris(triphenylphosphino)ruthenium (II) This compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.

A solution of RuCl2(PPh3)3 (0.200g; 0.21mmol) and ligand 1 (0.135g; 0.42mmol) in benzene (5mL) was stirred at 60C for 2h under the nitrogen atmosphere. Yellow crystals formed. The precipitate was filtered, washed with a small portion of hexane and dried. (0.154g; 90%). 1H NMR (400MHz, CD2Cl2): delta=11.45 (s, 2H, NH), 7.71-7.60 (m, J=11.6, 7.9Hz, 4H, Ph), 7.60-7.51 (m, J=7.6Hz, 2H, Ph), 7.52-7.43 (m, J=6.5Hz, 4H, Ph), 7.39-7.33 (m, 8H, ArH and CH), 7.34-7.26 (m, 4H, Ph), 7.26-7.17 (m, J=7.3Hz, 4H, Ph), 7.03-6.92 (m, J=5.4Hz, 6H, Ph), 6.81-6.70 (m, J=7.3Hz, 4H, Ph), 6.40-6.28 (m, J=8.7Hz, 6H, Ph), 3.77-3.61 (m, 2H, CH2), 3.45-3.31 (m, 2H, CH2), 1.46 (s, 18H, CH3); 13C NMR was not obtained due to the low solubility of this complex; 31P NMR (162MHz, CDCl3): delta=67.9 (s, 2P, ligand 1) ppm; C40H46Cl2N4P2Ru: calcd. C 58.82, H 5.68, N 6.86; found C 58.91, H 5.86, N 6.46.

With the complex challenges of chemical substances, we look forward to future research findings about Dichlorotris(triphenylphosphino)ruthenium (II)

Reference£º
Article; Alshakova, Iryna D.; Korobkov, Ilya; Kuzmina, Lyudmila G.; Nikonov, Georgii I.; Journal of Organometallic Chemistry; vol. 853; (2017); p. 68 – 73;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product.10049-08-8, name is Ruthenium(III) chloride An updated downstream synthesis route of 10049-08-8 as follows., 10049-08-8

Example 13 Synthesis of (3S)-3-(1,3-benzodioxol-5-yl)-3-[({1-[2-oxo-3-(phenylmethyl)-1(2H)-pyridinyl]cyclohexyl}carbonyl)amino]propanoic Acid Step One: To a solution of 3-benzylpyridine (1.65 g, 9.77 mmol) in acetone (3.5 mL), 1-chloro-2,4-dinitrobenzene (2.00 g, 9.56 mmol) was added and the mixture was refluxed overnight. The mixture was cooled to room temperature, diluted with acetone and the solvent was decanted from the precipitate. The crude solid was washed with acetone (2 times) and diethyl ether (1 time), decanting each time to give 37(3.57 g, 100percent) as a gray solid. Step Two: To a solution of 1-amino-1-hydroxymethylcyclohexane (0.45 g, 3.5 mmol) in n-butanol (8.75 mL), solid N-(2,4-dintrophenyl)-3-benzylpyridinum chloride (37, 1.23 g, 3.3 mmol) was added. The resulting solution was heated to reflux for 2.5 days under a nitrogen atmosphere. The mixture was cooled, diluted with water and filtered. The filtrate was basified with concentrated NH4OH (2 mL) and extracted with ethyl acetate. The aqueous layer was concentrated to dryness to give 38(0.56 g) as a yellow oil which was used without further purification. Step Three: To a solution of crude 38(0.56 g, 3.5 mmol theoretical) in water (10 mL), a solution of potassium ferricyanide (3.3 g, 10 mmol) in water (15 mL) was added dropwise via an addition funnel over 30 minutes at 0¡ã C. A solution of KOH (0.76 g, 13.5 mmol) in water (5 mL) was then added over 30 minutes. Toluene (10 mL) was added and the solution was stirred for one hour at 0¡ã C. The layers were separated, and the aqueous layer was extracted again with toluene. The combined extracts were dried over Na2SO4 and filtered and the filtrate was concentrated under reduced pressure. The residue was chromatographed on silica gel, eluding with 7:13 hexanes:ethyl acetate to give 39(20 mg, 1.9percent, two steps.) Step Four: To a suspension of 39(20 mg, 0.068 mmol) in aqueous KOH (1M, 0.70 mL) potassium persulfate (0.073 g, 0.270 mmol) and ruthenium (III) chloride (1 mg, catalytic) and THF (0.25 mL) were added. The mixture was stirred for 1 hour and extracted with dichloromethane. The aqueous layer was acidified and extracted with ethyl acetate (3 times). The ethyl acetate extracts were combined, dried over MgSO4 and filtered. The filtrate was concentrated under reduced pressure to give 40(0.0148 g, 70percent) as a tan solid. (3S)-3-(1,3-Benzodioxol-5-yl)-3-[({1-[2-oxo-3-(phenylmethyl)-1(2H)-pyridinyl]cyclohexyl}carbonyl)amino]propanoic acid was prepared from 40according to the procedures described in Example 1. 1H NMR (400 MHz, CD3SO2CD3): delta 1.40 (m, 4H), 1.68 (m, 2H), 2.04 (m, 2H), 2.60 (d, J=7.0 Hz, 2H), 3.67 (d, J=15.2 Hz, 1H), 3.72 (d, J=15.2 Hz, 1H), 5.12 (m, 1H), 5.95 (m, 2H), 6.19 (t, J=7.0 Hz, 1H), 6.74 (dd, J=7.8, 1.4 Hz, 1H), 6.76 (d, J=7.8 Hz, 1H), 6.90 (d, J=1.4 Hz, 1H), 7.10 (d, J=5.8 Hz, 1H), 7.20 (m, 5H), 7.57 (d, J=8.4Hz, 1H), 7.66 (dd, J=7.7, 1.8 Hz, 1H).

As the paragraph descriping shows that 10049-08-8 is playing an increasingly important role.

Reference£º
Patent; Biediger, Ronald J.; Dupre, Brian; Hamaker, Linda K.; Holland, George W.; Kassir, Jamal M.; Li, Wen; Market, Robert V.; Nguyen, Noel; Scott, Ian L.; Wu, Chengde; Decker, E. Radford; US2003/199692; (2003); A1;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI