In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product.246047-72-3, name is (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium An updated downstream synthesis route of 246047-72-3 as follows., 246047-72-3
Grubbs’ second generation catalyst (226 mg, 1 eq) and copper (I) chloride (26 mg, 1 eq) were charged in a Schlenk tube and degassed. A degassed solution of compound C4 (26 mg, 21 eq.) in anhydrous dichloromethane (50 mL) was transferred via cannula to the solid. The mixture was heated at 30 C. for 60 min. The solvent was removed in vacuo and the residue was purified by chromatography on silica gel (PE/EA) to afford compound C5 (202 mg) as a green solid in 100% yield. 31P NMR (CDCl3, 161.8 MHz) delta (ppm) 22.88 (s, 1P); HRMS (ES+): m/z=764 (M+H+).
With the complex challenges of chemical substances, we look forward to future research findings about 246047-72-3,belong ruthenium-catalysts compound
Reference£º
Patent; Idenix Pharmaceuticals, Inc.; Parsy, Christophe Claude; Alexandre, Francois-Rene; Bonnaterre, Florence Marie-Emilie; Surleraux, Dominique; US9115095; (2015); B2;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI