Day: October 15, 2020

246047-72-3, (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium is a ruthenium-catalysts compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: To a Schlenk flask charged with Grubbs? catalyst 2 (0.42 g,0.50 mmol) and CuCl (0.05 g, 0.50 mmol), compound 14 (or 15, 16)(0.6 mmol) in 10 mL dry dichloromethane was added at room temperature under N2. The resulting mixture was stirred for 40 min at 40 C. After being cooled to room temperature, the reaction mixturewas filtered and the clear filtrate was collected. The solvent from the filtrate was evaporated under vacuum to give a residue. The residue was purified by silica gel chromatography (CH2Cl2:ethyl acetate 2:1 or pentanes: ethyl acetate 3:2 or 1:1) to givethe desired product as a green crystalline solid., 246047-72-3

As the paragraph descriping shows that 246047-72-3 is playing an increasingly important role.

Reference£º
Article; Zhang, Yiran; Shao, Mingbo; Zhang, Huizhu; Li, Yuqing; Liu, Dongyu; Cheng, Yu; Liu, Guiyan; Wang, Jianhui; Journal of Organometallic Chemistry; vol. 756; (2014); p. 1 – 9;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

As a common heterocyclic compound, it belongs to quinuclidine compound,Quinuclidine-4-carboxylic acid hydrochloride,40117-63-3,Molecular formula: C8H14ClNO206,mainly used in chemical industry, its synthesis route is as follows.,246047-72-3

General procedure: To a Schlenk flask charged with Grubbs? catalyst 2 (0.42 g,0.50 mmol) and CuCl (0.05 g, 0.50 mmol), compound 14 (or 15, 16)(0.6 mmol) in 10 mL dry dichloromethane was added at room temperature under N2. The resulting mixture was stirred for 40 min at 40 C. After being cooled to room temperature, the reaction mixturewas filtered and the clear filtrate was collected. The solvent from the filtrate was evaporated under vacuum to give a residue. The residue was purified by silica gel chromatography (CH2Cl2:ethyl acetate 2:1 or pentanes: ethyl acetate 3:2 or 1:1) to givethe desired product as a green crystalline solid.

With the complex challenges of chemical substances, we look forward to future research findings about (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium,belong ruthenium-catalysts compound

Reference£º
Article; Zhang, Yiran; Shao, Mingbo; Zhang, Huizhu; Li, Yuqing; Liu, Dongyu; Cheng, Yu; Liu, Guiyan; Wang, Jianhui; Journal of Organometallic Chemistry; vol. 756; (2014); p. 1 – 9;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

Name is (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium, as a common heterocyclic compound, it belongs to ruthenium-catalysts compound, and cas is 246047-72-3, its synthesis route is as follows.,246047-72-3

After a 50 mL two-necked flask was purged with argon, the ligand 3cw (10 mmol), CuCl (30 mmol, 3 eq) and 30 mL of dry DCM were sequentially added and the mixture was purged three times with argon to protect the closed system with an argon balloon. Ruthenium complex 1b (12 mmol) was added under argon atmosphere, and the reaction was carried out at room temperature for 0.5 hour. After the reaction was over, silica gel was added to the filtrate after filtration to obtain sand. The crude product was obtained by silica gel column chromatography and then washed with methanol or pentane-DCM to obtain a green solid product 4cw, yield: 85%.

With the complex challenges of chemical substances, we look forward to future research findings about (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium

Reference£º
Patent; Zannan Science And Technology (Shanghai) Co., Ltd.; Zhan Zhengyun; (102 pag.)CN104262403; (2017); B;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

Dichlorotris(triphenylphosphino)ruthenium (II), cas is 15529-49-4, it is a common heterocyclic compound, the ruthenium-catalysts compound, its synthesis route is as follows.,15529-49-4

In a 3 L, 3-neck round bottom flask were added C959 (100.0 g, 104.2 mmol), 1,1- diphenyl-2-propyn-1-ol (24.9 g, 119.8 mmol), and triphenylphosphine (27.3 g, 104.2 mmol) under air. The flask was equipped with a thermocouple and rubber suba-seal septum and then it was placed under Ar using Schlenk technique. The reagents and products of this reaction are highly air sensitive in solution. A 1 L addition funnel was attached to the flask under a flow of Ar. To the addition funnel were added (2-Me)THF (1 L) and 4 M HC1 (25.6 mL, 104.2 mmol) in dioxane using Schlenk technique. The solution was added over 10 minutes at room temperature with stirring. Another 0.75 L (2-Me)THF were added directly to the flask. The addition funnel was replaced with a glass stopper under a flow of Ar and the flask was lowered into a pre-heated oil bath at 65 C. The reaction was monitored by 31P NMR. When conversion was deemed to be complete, the reaction flask was removed from the oil bath and hot filtered via cannula transfer through a celite pad (in an evacuated Schlenk filter) into a Schlenk flask. Approximately 85% (2- Me)THF was removed at room temperature (water bath) under vacuum. The resulting slurry was cooled to 0 C then filtered on a coarse glass frit under air. The solid was washed quickly with 3×50 mL portions of 0 C (2-Me)THF followed by hexanes (200 mL) (r.t.) and 2-propanol (100 mL). The solid from the frit was re-slurred with hexanes (200 mL) and filtered again. The solid was air-dried until no condensation was seen on the outside of the glass frit, then transferred to a 200 mL round bottom flask and dried under high vacuum overnight. The final ?H NMR andNIVIR in CDC13 indicate that the complex is a 1:1 adduct of (PPh3)2Ru(Phlnd)C12, and (2- Me)THF, C973, for a final molecular weight of 973 g/mol. Yield = 74.1 g (73%). 1H NMR (400 MFIz in CDC13 at r.t.): = 7.2-7.6 (overlapping CDC13 andaromatics), 7.07 (d, md, 1H), 6.62 (t, md, 1H), 6.43 (s, md, 1H), 3.92 (m, (2-Me)THF, 2H), 3.70(m, (2-Me)THF, 1H), 1.88-1.98 (overlapping m, (2-Me)THF, 3H), 1.41 (m, (2-Me)THF, 1H), 1.23(d, (2-Me)THF, 3H).

15529-49-4 is used more and more widely, we look forward to future research findings about Dichlorotris(triphenylphosphino)ruthenium (II)

Reference£º
Patent; MATERIA, INC.; CALIFORNIA INSTITUTE OF TECHNOLOGY; JOHNS, Adam, M.; HERRON, Jessica, R.; PEDERSON, Richard, L.; FIAMENGO, Bryan, A.; BEERMAN, Jennifer, A.; LIN, Tzu-Pin; CHU, Crystal, K.; GRUBBS, Robert, H.; (104 pag.)WO2018/75479; (2018); A1;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

As a common heterocyclic compound, it belongs to ruthenium-catalysts compound, name is (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium, and cas is 246047-72-3, its synthesis route is as follows.,246047-72-3

A 50 mL two-necked flask was purged with argon and then the ligand 7e (10 mmol), CuCl (30 mmol, 3 eq) and 30 mL of dry DCM were sequentially added and the mixture was purged three times with argon to protect the closed system with an argon balloon. Ruthenium complex 1b (12 mmol) was added under argon atmosphere, and the reaction was carried out at room temperature for 0.5 hour. After the reaction was over, silica gel was added to the filtrate to produce sand. The crude product was obtained by silica gel column chromatography and then washed with methanol or pentane-DCM to obtain a green solid product 8e with a yield of 74%.

With the complex challenges of chemical substances, we look forward to future research findings about 246047-72-3,belong ruthenium-catalysts compound

Reference£º
Patent; Zannan Science And Technology (Shanghai) Co., Ltd.; Zhan Zhengyun; (102 pag.)CN104262403; (2017); B;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.15529-49-4,Dichlorotris(triphenylphosphino)ruthenium (II),as a common compound, the synthetic route is as follows.

A 50 ml three-necked flask equipped with a stirring reflux device was charged with 1 mmol of 2-diphenylphosphineaniline, 1.5 mmol of p-bromobenzyl alcohol, 1 mmol of bis Dicyclohexylphosphine propane,mmol RuCl2 (PPh3) 3,1 mmol potassium hydroxide, 20 ml dioxane, the temperature was 110 C, heated for 20h under a nitrogen atmosphere, cooledHowever, filtration and recrystallization of the resulting solid from a mixed solvent of CH 2 Cl 2 and petroleum ether gave product 6 in a yield of 87%.

15529-49-4, The synthetic route of 15529-49-4 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; Luoyang Normal College; Li Hongmei; Xu Chen; Zu Enpu; Xiao Zhiqiang; Han Xin; (12 pag.)CN104804048; (2017); B;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

As a common heterocyclic compound, it belongs to quinuclidine compound,Quinuclidine-4-carboxylic acid hydrochloride,40117-63-3,Molecular formula: C8H14ClNO245,mainly used in chemical industry, its synthesis route is as follows.,246047-72-3

After a 50 mL two-necked flask was purged with argon, the ligand 3m (10 mmol), 30 mL of CuCl (30 mmol, 3 eq) and 30 mL of dry DCM were sequentially added and the mixture was purged three times with argon to protect the closed system with argon balloon. Ruthenium complex 1b (12 mmol) was added under argon atmosphere, and the reaction was carried out at room temperature for 0.5 hour. After the reaction was over, silica gel was added to the filtrate after filtration to obtain sand. The crude product was obtained by silica gel column chromatography and then washed with methanol or pentane-DCM to obtain a green solid product 4m. The yield was 84%.

With the complex challenges of chemical substances, we look forward to future research findings about (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium,belong ruthenium-catalysts compound

Reference£º
Patent; Zannan Science And Technology (Shanghai) Co., Ltd.; Zhan Zhengyun; (102 pag.)CN104262403; (2017); B;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

Name is Dichlorotris(triphenylphosphino)ruthenium (II), as a common heterocyclic compound, it belongs to ruthenium-catalysts compound, and cas is 15529-49-4, its synthesis route is as follows.,15529-49-4

To a slurry of HimtMPh (38 mg, 0.20 mM) and MeONa (10.8 mg, 0.20 mM) in tetrahydrofuran(THF) (5 mL) was added a solution of [RuCl2(PPh3)3] (96 mg, 0.10 mM) in THF(10 mL). The mixture was stirred for 8 h at room temperature. The solvent was removed invacuo, and the residue was washed with hexane. The residue was extracted with dichloromethaneand filtered; the solvent was removed in vacuo and further recrystallized fromCH2Cl2/EtOH/Et2O at room temperature. Block orange crystals of 1¡¤EtOH suitable for Xraydiffraction were obtained in a week. Yield: 90 mg, 86%. 31P NMR (CDCl3): 29.2, 55.6 ppm. 1H NMR (CDCl3): 1.25 (EtOH), 2.35 (s, Me, 6H), 3.72 (EtOH), 6.31 (s, imt-CH, 2H), 6.50 (d, imt-CH, J = 1.6 Hz, 2H), 6.96-6.70 (m, 12H), 7.09-7.13 (m, 6H), 7.19(d, C6H4, J = 8.0 Hz, 4H), 7.26-7.30 (m, 16H) ppm. IR (KBr disk, cm1): 3052 (w), 1634(m), 1595 (m), 1499 (s), 1432 (s), 1362 (s), 1263 (s), 1098 (s), 1031 (s), 805 (s), 694 (s),538 (s), 524 (s), 500 (m). MS (FAB): m/z 1052 [M+], 790 [M+ – PPh3], 528 [M+ -2PPh3]. Anal. Calcd for C56H48N4P2S2Ru¡¤(C2H6O) (%): C, 66.20; H, 5.36; N, 5.32.Found: C, 66.11; H, 5.34; N, 5.35

With the complex challenges of chemical substances, we look forward to future research findings about Dichlorotris(triphenylphosphino)ruthenium (II)

Reference£º
Article; Qin, Yi; Ma, Qing; Jia, Ai-Quan; Chen, Qun; Zhang, Qian-Feng; Journal of Coordination Chemistry; vol. 66; 8; (2013); p. 1405 – 1415;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

It is a common heterocyclic compound, the ruthenium-catalysts compound, (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium, cas is 246047-72-3 its synthesis route is as follows.,246047-72-3

Example 52 Synthesis of Ru complex 6a To a 50 mL two-necked round bottom flask, after filling with Ar atmosphere, were added ligand 5a (l .Ommol) and CuCl (3.0mmol, 3eq) and 30 mL dry DCM, followed by refilling with Ar three times and protected with Ar balloon in close system. Ru complex lb (l.Ommol) was added under Ar protection, and the mixture was stirred for 0.5 hr at room temperature. After the reaction was complete, the solution was filtered and the filtrate was concentrated and slurred with silica gel. The crude was obtained by silica gel column chromatography and washed with methanol or pentane-DCM to obtain 453mg of yellow-green solid product 6a, yield: 79%. Ru complex (6a) 1HNMR (400 MHz, CDC13): delta 18.53 (s, 1H, Ru=CH), 8.59 (s, 1H), 7.28-6.49 (m, 11H), 4.160 (s, 4H, NCH2CH2N), 2.50 (s, 12H), 2.42 (s, 6H).; Example 59 Synthesis of Ru complex 6h The synthetic procedure is the same as in Example 52 in 1.0 mmol scale. 106 mg of yellow-green solid product 6h was obtained (37% yield). Ru complex (6h) 1HNMR (400 MHz, CDC13): delta 16.52 (s, 1H, Ru=CH), 8.43 (s,1H, N=CH), 8.10 (s, 1H), 7.46-7.22 (m, 2H), 7.73-6.96 (m, 8H), 4.19 (s, 4H, NCH2CH2N), 3.95 (s, 3H), 3.87 (s, 3H), 2.49 (s, 12H), 2.48 (s, 6H).

With the complex challenges of chemical substances, we look forward to future research findings about (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium

Reference£º
Patent; ZANNAN SCITECH CO., LTD.; ZHAN, James Zheng-Yun; WO2011/79439; (2011); A1;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

Name is (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium, as a common heterocyclic compound, it belongs to ruthenium-catalysts compound, and cas is 246047-72-3, its synthesis route is as follows.,246047-72-3

Synthesis and characterization of [(IMesH2)(PCy3)(Cl)2Ru?CF2]: A solution of 0.32 g (0.37 mmol) [(IMesH2)(PCy3)(Cl)2Ru?CHPh] (5) in dry, degassed benzene (15 mL) in a thick-walled glass ampule was put under 1.5 atm of 1,1-difluoroethylene. The reaction was heated at 60 C. for 12 hrs, during which time it changed from reddish to brown in color. The solution was then concentrated to 5 mL and purified by column chromatography in air (silica gel, 5:1 pentane/THF). The orange fraction was stripped of solvent and dried under vacuum: yield 0.26 g (86%). 1H NMR (499.852 MHz, 25 C., CD2Cl2): delta 1.118 [br, 15H, PCy3], 1.626 [br, 15H, PCy3], 2.248 [s, 3H, p-CH3 of Mes], 2.285 [s, 3H, p-CH3 of Mes], 2.385 [m, 3H, PCy3], 2.480 [s, 6H, o-CH3 of Mes], 2.551 [s, 6H, o-CH3 of Mes], 4.003 [s, 4H, NCH2CH2N], 6.921 [s, 4H, m-H of Mes]. 13C {1H} NMR (125.705 MHz, 30 C., C6D6): delta 19.44 [s, CH3 of Mes], 20.65 [s, CH3 of Mes], 21.49 [s, CH3 of Mes], 21.50 [s, CH3 of Mes], 26.92 [d, J=1.3 Hz, PCy3], 28.50 [d, J=10 Hz, PCy3], 30.14 [s, PCy3], 33.34 [d, J=18 Hz, PCy3], 51.86 [d, 4 JPC=2.6 Hz, NCH2CH2N], 52.61 [d, 4JPC=3.5 Hz, NCH2CH2N], 127.30 [s, Mes], 128.17 [s, Mes], 129.26 [s, Mes], 129.51 [s, Mes], 130.11 [s, Mes], 130.52 [s, Mes], 134.68 [d, 4 JPC=0.7 Hz, ipso-C of Mes], 136.85 [s, ipso-C of Mes], 138.91 [s, Mes], 138.93 [s, Mes], 139.03 [s, Mes], 139.67 [s, Mes], 217.23 [d, 2JCP=87 Hz, NCN], 218.09 [td, 2JCP=12 Hz, 1 JCF=430 Hz, Ru?CF2]. 19F NMR (282.192 MHz, 25 C., CD2Cl2): delta 133.74 [d, 3JFP=4.5 Hz]. 31P {1H} NMR (121.392 MHz, 25 C., CD2Cl2): delta 32.15 (t, 3 JPF=4.4 Hz]. IR (KBr pellet): 1167 and 1172 (nuC-F).

With the complex challenges of chemical substances, we look forward to future research findings about (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium

Reference£º
Patent; CALIFORNIA INSTITUTE OF TECHNOLOGY; Grubbs, Robert H.; Chatterjee, Arnab K.; Choi, Tae-Lim; Goldberg, Steven D.; Love, Jennifer A.; Morgan, John P.; Sanders, Daniel P.; Scholl, Matthias; Toste, F. Dean; Trnka, Tina M.; (27 pag.)US9403854; (2016); B2;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI