Month: September 2020

A common heterocyclic compound, the ruthenium-catalysts compound, name is Dichlorotris(triphenylphosphino)ruthenium (II),cas is 15529-49-4, mainly used in chemical industry, its synthesis route is as follows.,15529-49-4

(PPh3)3RuCI2 (1 eq., 0.575 g, 0.6 mmol) and 1-(4-fluorophenyl)-1-phenylprop-2-yn-1-ol (compound 16A, 1.5 eq., 0.20 g, 0.9 mmol) were added in 4 ml HCI/dioxane solution (0.15 mol/l). The solution was heated to 90C for 3 hour, after which the solvent was removed under vacuum. Hexane (20 ml) was added to the flask and the solid was ultrasonically removed from the wall. The resulting suspension was filtered and washed two times using hexane (5 ml). The remaining solvent was evaporated affording a red-brown powder; 0.49 g (Yield: 90%). The product was characterized by NMR spectra 31P.31P NMR (121.49 MHz, CDCI3): 628.26.

As the rapid development of chemical substances, we look forward to future research findings about 15529-49-4

Reference£º
Patent; GUANG MING INNOVATION COMPANY (WUHAN); W.C. VERPOORT, Francis; YU, Baoyi; WO2014/108071; (2014); A1;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

A common heterocyclic compound, the ruthenium-catalysts compound, name is (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium,cas is 246047-72-3, mainly used in chemical industry, its synthesis route is as follows.,246047-72-3

After a 50 mL two-necked flask was replaced by argon, the ligand 5a (10 mmol), CuCl (30 mmol, 3 eq) and 30 mL of dry DCM were sequentially added and the mixture was purged three times with argon to protect the closed system with an argon balloon. Ruthenium complex 1b (12 mmol) was added under argon atmosphere, and the reaction was carried out at room temperature for 0.5 hour. After the reaction was completed, silica gel was added to the filtrate to produce sand. The crude product was obtained by silica gel column chromatography, and then washed with methanol or pentane-DCM to obtain yellow-green solid product 6a in a yield of 79%.

As the rapid development of chemical substances, we look forward to future research findings about 246047-72-3

Reference£º
Patent; Zannan Science And Technology (Shanghai) Co., Ltd.; Zhan Zhengyun; (102 pag.)CN104262403; (2017); B;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.246047-72-3,(1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium,as a common compound, the synthetic route is as follows.

246047-72-3, A suspension of 1.50 g (1.77 mmol) of [RuCl2(PCy3)(ImH2Mes)(phenylmethylene)] (commercially available from Sigma- Aldrich Inc., St. Louis, USA), 0.19 g (1.94 mmol) of copper chloride and 0.51 g (1.94 mmol) of N,N-diethyl-2-[((E,Z)-2-propenyl)-phenoxy]- propionamide as a 4: 1 mixture of E/Z-isomers in 1 10 ml of dichloromethane was stirred for 40 min at 400C. The reaction mixture was evaporated to dryness at 400C/ 10 mbar. The crude title product was purified by repeated digestion with ethylacetate / pentane / tetrahydrofuran to yield 0.73 g (58%) of the title compound as a green crystalline solid.MS: 711.2 (M+). Anal, calcd. for C35H45Cl2N3O2Ru: C, 59.06; H, 6.37; N, 5.90; Cl, 9.96. Found: C, 58.56; H, 6.44; N, 5.23; Cl, 9.86.Crystals of the title compound suitable for X-ray crystal structure analysis were grown by vapor diffusion of pentane into a solution of 20 mg of [RuCl2(=CH(o- OCH(Me)CONEt2)Ph)(ImH2MeS)] in 2 ml of tetrahydrofuran at room temperature.

246047-72-3 (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium 11147261, aruthenium-catalysts compound, is more and more widely used in various fields.

Reference£º
Patent; F. HOFFMANN-LA ROCHE AG; WO2009/124853; (2009); A1;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

15529-49-4, Dichlorotris(triphenylphosphino)ruthenium (II) is a ruthenium-catalysts compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

To a slurry of HtimAr (42 mg, 0.20 mmol) and MeONa (10.8 mg, 0.20 mmol) in THF (5 mL) was added a solution of [Ru(PPh3)3Cl2] (96 mg, 0.10 mmol) in THF (10 mL). The mixture was stirred for 4 h at room temperature. The solvent was removed in vacuo and the residue was washed with hexane and further recrystallized from CH2Cl2/hexane at room temperature. Block orange crystals of 2 suitable for X-ray diffraction were obtained in a week. Yield: 76 mg, 73% (based on Ru).

15529-49-4, 15529-49-4 Dichlorotris(triphenylphosphino)ruthenium (II) 11007548, aruthenium-catalysts compound, is more and more widely used in various fields.

Reference£º
Article; Zhu, Hang; Ma, Qing; Jia, Ai-Quan; Chen, Qun; Leung, Wa-Hung; Zhang, Qian-Feng; Inorganica Chimica Acta; vol. 405; (2013); p. 427 – 436;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.15529-49-4,Dichlorotris(triphenylphosphino)ruthenium (II),as a common compound, the synthetic route is as follows.

General procedure: The amine (4-CH3-pip, 4-CH2Ph-pip or 4-CH2(OH)-pip;0.34 mmol) was added to a solution of [RuCl2(PPh3)3] (0.26 mmol;0.25 g) in acetone (40 mL). The resulting dark green solution wasstirred for 2 h at RT. A green precipitate was formed, filtered,washed with methanol and ethyl ether, and then dried in vacuum.Complex 3 (R = OH): 67% yield. Analytical data for RuCl2P2NC42H43O are 62.15C, 5.34H, and 1.73% N; found 62.19C, 5.26H, and 1.83% N. FTIR in CsI: 323 for cm-1 for nu(Ru-Cl); 3230 cm-1 nu(N-H). 31P{1H} NMR in CDCl3: 62.7 ppm (s)., 15529-49-4

As the paragraph descriping shows that 15529-49-4 is playing an increasingly important role.

Reference£º
Article; Chaves, Henrique K.; Ferraz, Camila P.; Carvalho Jr., Valdemiro P.; Lima-Neto, Benedito S.; Journal of Molecular Catalysis A: Chemical; vol. 385; (2014); p. 46 – 53;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

246047-72-3, (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium is a ruthenium-catalysts compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

A suspension of 218 mg (0.26 mmol) of [RuCl2(PCy3) (ImH2Mes)(phenylmethy- lene)], 26 mg (0.26 mmol) copper chloride and 49 mg (0.29 mmol) 2-methyl-8-vinyl- quinoline in 17 ml methylene chloride was stirred at 300C for 90 min. The reaction mixture was evaporated to dryness and the isolated crude product purified by silica gel chromatography (hexane / ethyl acetat 7:3) and finally digested in 15 ml hexane at room temperature for 30 min to yield 157 mg (96%) of the title compound as green crystals. MS: 632.9 (M+). 1H-NMR (300 MHz, C6D6): 2.15 (s, 3H); 2.29 (s, 6H); 2.64 (s, 12H); 3.49 (s, 4H); 6.30 (d, J=8.4Hz, IH); 6.80 (t, J=7.3Hz, IH); 6.98 (s, 4H); 7.10 (d, J=8.4Hz, IH); 7.40 (d, J=8.1Hz, IH); 7.52 (d, J=7.0Hz, IH), 17.15-17.32 (br, IH). Anal, calcd. for C32H35N3Cl2Ru: C, 60.66; H, 5.57; N, 6.63; Cl, 11.19. Found: C, 60.33; H, 5.58; N, 6.27; Cl, 10.90., 246047-72-3

246047-72-3 (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium 11147261, aruthenium-catalysts compound, is more and more widely used in various fields.

Reference£º
Patent; F. HOFFMANN-LA ROCHE AG; WO2008/644; (2008); A1;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

15529-49-4, Dichlorotris(triphenylphosphino)ruthenium (II) is a ruthenium-catalysts compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

(PPh3)3RuCI2 (1 eq., 0.575 g, 0.6 mmol) and 1-2,6-dimethylphenyl-1-phenyl-prop-2-yn-1-ol (compound D, 1.5 eq., 0.213 g, 0.9 mmol) were added in 4 ml HCI/dioxane solution (0.15 mol/l). The solution was heated to 90C for 3 hour, after which the solvent was removed under vacuum. Hexane (20 ml) was added to the flask and the solid was ultrasonically removed from the wall. The resulting suspension was filtered and washed two times using hexane (5 ml). The remaining solvent was evaporated affording a red-brown powder; 0.50 g (Yield: 90%). The product was characterized by NMR spectra 31P.31P NMR (121.49 MHz, CDCI3): 629.64., 15529-49-4

15529-49-4 Dichlorotris(triphenylphosphino)ruthenium (II) 11007548, aruthenium-catalysts compound, is more and more widely used in various fields.

Reference£º
Patent; GUANG MING INNOVATION COMPANY (WUHAN); W.C. VERPOORT, Francis; YU, Baoyi; WO2014/108071; (2014); A1;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

246047-72-3, (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium is a ruthenium-catalysts compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

A suspension of 100 mg (0.12 mmol) of [RuCl2(PCy3) (ImH2Mes)(phenylmethy- lene)], 12 mg (0.12 mmol) copper chloride and 100 mg (0.12 mmol) 2-phenyl-8-vinyl- quinoline-4-ol in 11 ml methylene chloride was stirred at 400C for 1 h. The reaction mixture was evaporated to dryness and the isolated crude product purified by silica gel chromatography (hexane / ethyl acetat 2:1) to yield 51 mg (61%) of the title compound as green crystals. MS: 711.1 (M+). 1H-NMR (300 MHz, CD2Cl2): 2.32 (s, 12H); 2.41 (s, 6H); 3.90 (s, 4H); 6.12-6.28 (br, IH); 6.80-6.92 (m, 2H); 6.98 (s, 4H); 7.04-7.14 (m, IH); 7.19 (t, J=7.1Hz, IH); 7.29 (d, J=6.9Hz, IH); 7.35 (d, J=7.5Hz, 2H); 7.49 (d, J=7.1Hz, IH); 7.80-8.00 (br, IH); 17.34 (s, IH)., 246047-72-3

As the paragraph descriping shows that 246047-72-3 is playing an increasingly important role.

Reference£º
Patent; F. HOFFMANN-LA ROCHE AG; WO2008/644; (2008); A1;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

15529-49-4, Dichlorotris(triphenylphosphino)ruthenium (II) is a ruthenium-catalysts compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,15529-49-4

A solution of RuCl2(PPh3)3 (0.200g; 0.21mmol) and ligand 1 (0.135g; 0.42mmol) in benzene (5mL) was stirred at 60C for 2h under the nitrogen atmosphere. Yellow crystals formed. The precipitate was filtered, washed with a small portion of hexane and dried. (0.154g; 90%). 1H NMR (400MHz, CD2Cl2): delta=11.45 (s, 2H, NH), 7.71-7.60 (m, J=11.6, 7.9Hz, 4H, Ph), 7.60-7.51 (m, J=7.6Hz, 2H, Ph), 7.52-7.43 (m, J=6.5Hz, 4H, Ph), 7.39-7.33 (m, 8H, ArH and CH), 7.34-7.26 (m, 4H, Ph), 7.26-7.17 (m, J=7.3Hz, 4H, Ph), 7.03-6.92 (m, J=5.4Hz, 6H, Ph), 6.81-6.70 (m, J=7.3Hz, 4H, Ph), 6.40-6.28 (m, J=8.7Hz, 6H, Ph), 3.77-3.61 (m, 2H, CH2), 3.45-3.31 (m, 2H, CH2), 1.46 (s, 18H, CH3); 13C NMR was not obtained due to the low solubility of this complex; 31P NMR (162MHz, CDCl3): delta=67.9 (s, 2P, ligand 1) ppm; C40H46Cl2N4P2Ru: calcd. C 58.82, H 5.68, N 6.86; found C 58.91, H 5.86, N 6.46.

15529-49-4 Dichlorotris(triphenylphosphino)ruthenium (II) 11007548, aruthenium-catalysts compound, is more and more widely used in various fields.

Reference£º
Article; Alshakova, Iryna D.; Korobkov, Ilya; Kuzmina, Lyudmila G.; Nikonov, Georgii I.; Journal of Organometallic Chemistry; vol. 853; (2017); p. 68 – 73;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.246047-72-3,(1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium,as a common compound, the synthetic route is as follows.

To a solution of 13b (40.0 mg, 0.065 mmol) in anhydrous CH2Cl2 (6.0 ml) was added2nd generation Grubbs catalyst (50.3 mg, 0.059 mmol) and CuCl (I) (13.0 mg, 0.13mmol) under nitrogen at 30 C and stirred for 3 h. The reaction mixture was concentrated in vacuo, and the residue was purified by column chromatography onsilica gel (hexane / AcOEt = 2 / 1) to give 3b (55.5 mg, 78%).green crystals; mp 160-165 C (dec.); 1H NMR (270 MHz, CDCl3) delta 2.01-2.04 (m, 2H),2.22-2.31 (m, 2H), 2.43 (d, J = 14.8 Hz, 18H), 2.77-2.87 (m, 4H), 4.10-4.21 (m, 6H),6.51 (s, 1H), 7.08 (s, 5H), 16.43 (s, 1H); 19F NMR (466 MHz, CDCl3) delta -80.5 (3F),-114.4 (2F), -121.5 (2F), -121.8 (4F), -122.5 (2F), -123.3 (2F), -126.0 (2F); 13C NMR(68 MHz, CDCl3) delta 19.2, 21.0, 22.5, 23.5, 51.7, 69.5, 77.5, 118.9, 124.1, 128.9, 129.5,133.2, 136.3, 138.7, 143.7, 148.5, 210.7, 291.4; IR (FT) 3905, 3857, 3816, 3743, 3700,3642, 3616, 3569, 3013, 2945, 2913, 2856, 2363, 2331, 1738, 1691, 1596, 1555, 1476,1455, 1413, 1245, 1203, 1140, 1108, 1035, 993, 915, 857, 814, 730 cm-1; HRMS (FAB)m/z [M+H]+ calcd for C41H40Cl2F17N2ORu 1072.1290, found 1072.1320.

246047-72-3, The synthetic route of 246047-72-3 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Kobayashi, Yuki; Suzumura, Naoki; Tsuchiya, Yuki; Goto, Machiko; Sugiyama, Yuya; Shioiri, Takayuki; Matsugi, Masato; Synthesis; vol. 49; 8; (2017); p. 1796 – 1807;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI