Day: September 25, 2020

(1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium, cas is 246047-72-3, it is a common heterocyclic compound, the ruthenium-catalysts compound, its synthesis route is as follows.,246047-72-3

A suspension of 1.00 g (1.18 mmol) of [RuCl2(PCy3)(ImH2Mes)(phenylmethylene)] (commercially available from Sigma- Aldrich Inc., St. Louis, USA), 0.14 g (1.41 mmol) of copper chloride and 0.37 g (1.41 mmol) of 2-methyl-l-pyrrolidin-l-yl-2-(2-vinyl-phenoxy)- propan-1-one in 80 ml of dichloro methane was stirred for 90 min at 400C. The reaction mixture was evaporated to dryness at 40C/10 mbar. The residue was stirred in 25 ml of ethyl acetate for 15 min at room temperature. The dark green suspension was filtered and the filtrate concentrated to a total volume of 5 ml. To the green solution, 15 ml of pentane were added and the formed suspension was stirred for 30 min at room temperature and filtered. The filter cake was washed with 40 ml of pentane and dried at 25C/10 mbar over night to afford 0.68 g (80% yield) of the title compound as a green powder.MS: 723.2 (M+).

As the rapid development of chemical substances, we look forward to future research findings about 246047-72-3

Reference£º
Patent; F. HOFFMANN-LA ROCHE AG; WO2009/124853; (2009); A1;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

Dichlorotris(triphenylphosphino)ruthenium (II), cas is 15529-49-4, it is a common heterocyclic compound, the ruthenium-catalysts compound, its synthesis route is as follows.,15529-49-4

Under argon dichlorotris(triphenylphosphine)ruthenium(II) (1.52 g, 1.58 mmol) is added to a solution of N-(2-(diphenylphosphino)benzylidene)-2-(ethylthio)ethanamine (0.60 g, 1.58 mmol) in toluene (13 ml). After stirring for 19 h at 110 C. the reaction mixture is cooled to room temperature and evaporated under vacuo to a volume of 5 ml. To this red suspension DCM (20 ml) is added. After stirring for 15 min the suspension is filtered and dried under vacuo. Complex 6 is obtained as a red solid (0.88 g, 69%). Analytical data: 1H-NMR (400 MHz, CDCl3): 8.80 (d, J=8.84, 1H), 7.56-6.81 (m, 29H), 6.35 (m, 2H), 4.60 (m, 1H), 4.20 (m, 1H), 3.03 (m, 2H), 2.29 (m, 1H), 0.92 (t, J=7.33, 3H). 31P-NMR (500 MHz, CDCl3): 45.68 (d, J=30.23, 1P), 29.60 (d, J=30.23, 1P). MS (ESI): 811.10 (40%, M+), 776.12 (100%, [M-Cl]+). Anal. calcd. for C41H39Cl2NP2RuS: C, 60.66%; H, 4.84%; N, 1.73%. Found: C, 60.85%; H, 4.90%; N, 1.64%

As the rapid development of chemical substances, we look forward to future research findings about 15529-49-4

Reference£º
Patent; GIVAUDAN SA; GEISSER, Roger Wilhelm; OETIKER, Juerg Daniel; SCHROeDER, Fridtjof; (17 pag.)US2016/326199; (2016); A1;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.15529-49-4,Dichlorotris(triphenylphosphino)ruthenium (II),as a common compound, the synthetic route is as follows.

Compound 10 (628.5 mg, 1.0 mmol) and degassed morpholine (15 mL) were placed in a 100-mL Young-Schlenk container substituted with argon gas. Thereafter, the Young-Schlenk container was placed in an oil bath, and heated to 120 C. while stirring the components in the Young-Schlenk container, thereby causing a reaction. The progress of the reaction was confirmed by TLC, and the heating was stopped after two hours. Subsequently, the morpholine in the reaction mixture restored to room temperature (25 C.) was removed after collection with a liquid nitrogen trap under reduced pressure (0.1 to 2 mmHg). At this time, the reaction mixture was sufficiently stirred, and the Young-Schlenk container was immersed in water at room temperature (25 C.) to prevent cooling of the Young-Schlenk container by the heat of vaporization. (0255) After sufficiently removing the morpholine, dichlorotris(triphenylphosphino)ruthenium (II) (958.8 mg, 1.0 mmol) and dehydrated toluene (20 mL) were added while introducing argon gas into the container, and the mixture was heated to 110 C. using an oil bath, thereby causing a reaction. The heating was stopped after two hours, and the reaction mixture was restored to room temperature (25 C.). (0256) Subsequently, dehydrated hexane (40 mL) was added to the reaction mixture in an argon gas atmosphere. Thereafter, the whole mixture, including the hexane layer and the toluene layer, in the Young-Schlenk container was stirred and completely mixed. After leaving the mixture unattended for an hour, the generated purple substance was filtered out in an argon atmosphere while being washed with dehydrated diethylether, thereby obtaining a crude product. (0257) Subsequently, the resulting crude product was subjected to column chromatography (developing solvent: chloroform/THF=10/1) in which silica gels were accumulated to about 10 cm, thereby removing a compound with high polarity. The effluent was collected to a flask and the collection was continued until the color of the purple liquid was slightly diluted. After this operation, the solution collected in the recovery flask was rapidly concentrated by an evaporator, thereby obtaining 563.7 mg (0.73 mmol, 73%) of substantially pure Compound 2f (RUPCY3) as a purple substance. (0258) The spectral data of Compound 2f (RUPCY3) is shown below. (0259) 1H NMR (600 MHz, CDCl3): delta 8.12 (d, 2H, J=8.2 Hz, C12H6N2), 7.86 (d, 2H, J=8.2 Hz, C12H6N2), 7.80 (s, 2H, C12H6N2), 4.05 (d, 4H, J 35=7.6 Hz, PCH2), 2.42-2.51 (br, 4H, C6H11), 2.31 (d, 4H, J=11.0 Hz C6H11), 2.12 (d, 4H, J=12.4 Hz, C6H11), 1.61-1.94 (m, 20H, C6H11), 1.18-1.37 (m, 12H, C6H11). 13C NMR (151 MHz, CDCl3): delta 163.6, 149.3, 132.6, 128.6, 125.3, 121.8, 41.4, (d, 1JPC=23.1 Hz) 36.6 (t, 1JPC=7.2 Hz), 30.7, 29.4, 27.8, 27.6, 26.4. 31P{1H} NMR (243 MHz, CDCl3): delta 56.8. HRMS (ESI, (M-Cl)+) Calcd for C38H54ClN2P2Ru+: 737.2494. Found m/z=737.2483. (0260) FIG. 2 shows the result of an X-ray single crystal structural analysis (Oak Ridge Thermal Ellipsoid Plot) of Compound 2f., 15529-49-4

15529-49-4 Dichlorotris(triphenylphosphino)ruthenium (II) 11007548, aruthenium-catalysts compound, is more and more widely used in various fields.

Reference£º
Patent; National University Corporation Nagoya University; Saito, Susumu; Noyori, Ryoji; Miura, Takashi; Naruto, Masayuki; Iida, Kazuki; Takada, Yuki; Toda, Katsuaki; Nimura, Sota; Agrawal, Santosh; Lee, Sunkook; (42 pag.)US9463451; (2016); B2;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

246047-72-3, (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium is a ruthenium-catalysts compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

To a solution of 13a (22.0 mg, 0.038 mmol) in anhydrous CH2Cl2 (5.0 ml) was added2nd generation Grubbs catalyst (29.0 mg, 0.034 mmol) and CuCl (I) (7.5 mg, 0.075mmol) under nitrogen at 30 C and stirred for 3 h. The reaction mixture wasconcentrated in vacuo, and the residue was purified by column chromatography onsilica gel (hexane / CH2Cl2 = 1 / 1) to give 3a (14.0 mg, 35%).Green crystals; mp 178-183 C (dec.); 1H NMR (270 MHz, CDCl3) delta 2.09-2.00 (m, 2H),2.43 (d, J = 14.0 Hz, 18H), 2.86 (t, J = 12.1 Hz, 2H), 4.17 (s, 4H), 4.27 (t, J = 10.2 Hz,2H), 6.91 (s, 1H), 7.08 (s, 4H), 7.43 (s, 1H), 16.32 (s, 1H); 19F NMR (466 MHz, CDCl3)delta -80.5 (3F), -109.2 (2F), -121.0 (2F), -121.3 (2F), -121.7 (4F), -122.5 (2F), -126.0(2F); 13C NMR (68 MHz, CDCl3) delta 19.2, 21.0, 22.1, 23.6, 51.7, 70.2, 118.0, 123.3,124.2, 127.1, 129.6, 136.1, 138.7, 139.0, 142.8, 143.2, 151.8, 209.2, 288.5; IR (FT)3979, 3857, 3747, 3685, 3417, 2956, 2918, 2363, 2336, 1596, 1481, 1413, 1240, 1208,1140, 1046, 988, 904, 857, 809, 741, 720 cm-1; HRMS (FAB) m/z [M+H]+ calcd forC39H36Cl2F17N2ORu 1044.0977; found 1044.0991.

246047-72-3, As the paragraph descriping shows that 246047-72-3 is playing an increasingly important role.

Reference£º
Article; Kobayashi, Yuki; Suzumura, Naoki; Tsuchiya, Yuki; Goto, Machiko; Sugiyama, Yuya; Shioiri, Takayuki; Matsugi, Masato; Synthesis; vol. 49; 8; (2017); p. 1796 – 1807;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

15529-49-4, Dichlorotris(triphenylphosphino)ruthenium (II) is a ruthenium-catalysts compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: Diphosphine ligand (2.0 mmol) was dissolved in 10 mL of dichloromethane and the solution was added dropwise to a stirred solution of RuCl2(PPh3)3 (1.0 mmol) in 10 mL of dichloromethane. The reaction mixture was stirred approximately for 50 min at room temperature. The brown solution was filtered to remove the insoluble impurities. The solvent was reduced by a vacuum and the product was then precipitated by adding n-hexane. The yellow solid was filtered and washed three times with 20 mL of diethyl ether., 15529-49-4

As the paragraph descriping shows that 15529-49-4 is playing an increasingly important role.

Reference£º
Article; Al-Noaimi, Mousa; Warad, Ismail; Abdel-Rahman, Obadah S.; Awwadi, Firas F.; Haddad, Salim F.; Hadda, Taibi B.; Polyhedron; vol. 62; (2013); p. 110 – 119;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

(1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium, cas is 246047-72-3, it is a common heterocyclic compound, the ruthenium-catalysts compound, its synthesis route is as follows.,246047-72-3

Complex 1 (2.0 grams) was dissolved in toluene (10 mL), and 4-phenylpyridine (1.50 grams, 4 mol equivalents) was added. The reaction flask was purged with argon and the reaction mixture was stirred for approximately 12 hours at about 20 C. to about 25 C. during which time a color change from dark purple to dark green was observed. The reaction mixture was transferred into 75 mL of cold (about 0 C.) pentane, and a dark green solid precipitated. The precipitate was filtered, washed with 420 mL of cold pentane, and dried under vacuum to afford (IMesH2)(C11H9N)2(Cl)2Ru-CHPh 13 as a dark green powder (2.0 grams, 97% yield). [00135] 1H NMR (500 MHz, CD2Cl2): d19.23 (s, 1H, CHPh), 8.74 (br. s, 2H, pyridine), 7.91 (br. s, 2H, pyridine), 7.70-7.08 (multiple peaks, 19H, ortho CH, para CH, meta CH, pyridine), 6.93 (br. S, 2H, Mes CH) 6.79 (br. s, 2H, Mes CH), 4.05 (br. s, 4H, NCH2CH2N), 2.62-2.29 (multiple peaks, 18H, Mes CH3).

As the rapid development of chemical substances, we look forward to future research findings about 246047-72-3

Reference£º
Patent; California Institute of Technology; Cymetech, LLP; US6759537; (2004); B2;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.15529-49-4,Dichlorotris(triphenylphosphino)ruthenium (II),as a common compound, the synthetic route is as follows.

Example 6: Dichloro[(N-(2-(diphenylphosphino)benzylidene)-2-(ethylthio)ethanamine)- (triphenyl-phosphine)]-ruthenium(ll) (6): Under argon a solution of 2-(ethylthio)ethanamine (0.36 g, 3.44 mmol) in THF (3 ml) is added to a solution of 2-(diphenylphosphino)benzaldehyde (1.00 g, 3.44 mmol) in THF (10 ml). After stirring for 12 h at 72 C the reaction mixture is cooled to 0 C, DCM (3 ml) is added and the solvents are evaporated under vacuo. SNP-ligand N-(2- (diphenylphosphino)benzylidene)-2-(ethylthio)ethan-amine is obtained as an orange solid (1.20 g, 92%). Analytical data: 1H-NMR (400 MHz, CDCl3): 8.92 (d, 7=4.80, 1H), 8.00 (m, 1H), 7.41 (m, 1H), 7.38-7.28 (m, 11H), 6.91 (m, 1H), 3.70 (dt, 7=1.26, 7.07, 2H), 2.62 (t, 7=7.33, 2H), 2.50 (q, 7=7.33, 2H), 1.23 (t, 7=7.33, 3H). 13C-NMR (400 MHz, CDCl3): 161.12, 139.67, 137.93, 136.96, 136.87, 134.42, 133.77, 130.74, 129.28, 129.01, 128.13, 61.64, 32.56, 26.49, 15.28. 31P-NMR (500 MHz, CDCl3): -13.55 (s, IP). GC/MS: 377 (6%, M+), 348 (54%, [M-29]+), 288 (100%), 226 (20%), 208 (14%), 183 (28%), 165 (14%), 107 (11%), 89 (34%), 61 (14%). Under argon dichlorotris(triphenylphosphine)ruthenium(ll) (1.52 g, 1.58 mmol) is added to a solution of N-(2-(diphenylphosphino)benzylidene)-2-(ethylthio)ethanamine (0.60 g, 1.58 mmol) in toluene (13 ml). After stirring for 19 h at 110 C the reaction mixture is cooled to room temperature and evaporated under vacuo to a volume of 5 ml. To this red suspension DCM (20 ml) is added. After stirring for 15 min the suspension is filtered and dried under vacuo. Complex 6 is obtained as a red solid (0.88 g, 69%). Analytical data: 1H-NMR (400 MHz, CDCl3): 8.80 (d, 7=8.84, 1H), 7.56-6.81 (m, 29H), 6.35 (m, 2H), 4.60 (m, 1H), 4.20 (m, 1H), 3.03 (m, 2H), 2.29 (m, 1H), 0.92 (t, 7=7.33, 3H). 31P-NMR (500 MHz, CDCl3): 45.68 (d, 7=30.23, 1P), 29.60 (d, 7=30.23, IP). MS (ESI): 811.10 (40%, M+), 776.12 (100%, [M-Cl]+). Anal, calcd. for C41H39Cl2NP2RUS: C, 60.66 %; H, 4.84 %; N, 1.73 %. Found: C, 60.85 %; H, 4.90 %; N, 1.64 %.

15529-49-4, As the paragraph descriping shows that 15529-49-4 is playing an increasingly important role.

Reference£º
Patent; GIVAUDAN SA; GEISSER, Roger Wilhelm; OETIKER, Juerg Daniel; SCHROeDER, Fridtjof; WO2015/110515; (2015); A1;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.246047-72-3,(1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium,as a common compound, the synthetic route is as follows.

After a 50 mL two-necked flask was purged with argon, the ligand 3m (10 mmol), 30 mL of CuCl (30 mmol, 3 eq) and 30 mL of dry DCM were sequentially added and the mixture was purged three times with argon to protect the closed system with argon balloon. Ruthenium complex 1b (12 mmol) was added under argon atmosphere, and the reaction was carried out at room temperature for 0.5 hour. After the reaction was over, silica gel was added to the filtrate after filtration to obtain sand. The crude product was obtained by silica gel column chromatography and then washed with methanol or pentane-DCM to obtain a green solid product 4m. The yield was 84%.

246047-72-3, 246047-72-3 (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium 11147261, aruthenium-catalysts compound, is more and more widely used in various fields.

Reference£º
Patent; Zannan Science And Technology (Shanghai) Co., Ltd.; Zhan Zhengyun; (102 pag.)CN104262403; (2017); B;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.15529-49-4,Dichlorotris(triphenylphosphino)ruthenium (II),as a common compound, the synthetic route is as follows.

(PPh3)3RuCI2 (1 eq., 0.575 g, 0.6 mmol) and 1-c-hexyl-1-phenyl-prop-2-yn-1-ol (compound E, 1.5 eq., 0.19 g, 0.9 mmol) were added in 4 ml HCI/dioxane solution (0.15 mol/l). The solution was heated to 90C for 3 hour, after which the solvent was removed under vacuum. Hexane (20 ml) was added to the flask and the solid was ultrasonically removed from the wall. The resulting suspension was filtered and washed two times using hexane (5 ml). The remaining solvent was evaporated affording a red-brown powder; 0.51 g (Yield: 95 %). The product was characterized by NMR spectra 31P.31P NMR (121.49 MHz, CDCI3): 629.64., 15529-49-4

The synthetic route of 15529-49-4 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; GUANG MING INNOVATION COMPANY (WUHAN); W.C. VERPOORT, Francis; YU, Baoyi; WO2014/108071; (2014); A1;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.246047-72-3,(1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium,as a common compound, the synthetic route is as follows.

General procedure: To a Schlenk flask charged with Grubbs? catalyst 2 (0.42 g,0.50 mmol) and CuCl (0.05 g, 0.50 mmol), compound 14 (or 15, 16)(0.6 mmol) in 10 mL dry dichloromethane was added at room temperature under N2. The resulting mixture was stirred for 40 min at 40 C. After being cooled to room temperature, the reaction mixturewas filtered and the clear filtrate was collected. The solvent from the filtrate was evaporated under vacuum to give a residue. The residue was purified by silica gel chromatography (CH2Cl2:ethyl acetate 2:1 or pentanes: ethyl acetate 3:2 or 1:1) to givethe desired product as a green crystalline solid., 246047-72-3

246047-72-3 (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium 11147261, aruthenium-catalysts compound, is more and more widely used in various fields.

Reference£º
Article; Zhang, Yiran; Shao, Mingbo; Zhang, Huizhu; Li, Yuqing; Liu, Dongyu; Cheng, Yu; Liu, Guiyan; Wang, Jianhui; Journal of Organometallic Chemistry; vol. 756; (2014); p. 1 – 9;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI