Brief introduction of 246047-72-3

246047-72-3, As the paragraph descriping shows that 246047-72-3 is playing an increasingly important role.

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.246047-72-3,(1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium,as a common compound, the synthetic route is as follows.

A suspension of 1.00 g (1.18 mmol) of [RuCl2(PCy3)(ImH2Mes)(phenylmethylene)] (commercially available from Sigma- Aldrich Inc., St. Louis, USA), 0.13 g (1.30 mmol) of copper chloride and 0.36 g (1.30 mmol) of 2-[((?,Z)-2-propenyl)-phenoxy]-l -pyrrolidine- 1-yl- propan-1-one as a 4:1 mixture ofE/Z-isomers in 75 ml of dichloromethane was stirred for 30 min at 400C. The reaction mixture was evaporated to dryness at 400C/ 10 mbar. The residue was stirred in 60 ml of ethyl acetate for 30 min at room temperature. The dark green suspension was filtered and the filtrate was evaporated to dryness at 40C/10 mbar. The crude title product was purified by silica gel chromatography (dichloromethane/methanol 98:2) to yield 0.52 g (62% yield) of the title compound as a green powder.MS: 709.2 (M+). Anal, calcd. for C35H43Cl2N3O2Ru ? 0.85 CH2Cl2: C, 55.04; H, 5.76; N, 5.37, Cl 16.83. Found: C, 54.52; H, 5.74; N, 5.29, Cl 16.82.

246047-72-3, As the paragraph descriping shows that 246047-72-3 is playing an increasingly important role.

Reference£º
Patent; F. HOFFMANN-LA ROCHE AG; WO2009/124853; (2009); A1;,
Highly efficient and robust molecular ruthenium catalysts for water oxidation
Catalysts | Special Issue : Ruthenium Catalysts – MDPI